SCHEMBL7724562

SCHEMBL7724562

CCC(=O)Oc1ccc(S(=O)(=O)C(=[N+]=[N-])S(=O)(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.51
ESR1 P03372 2/20 0.44
HIF1A Q16665 2/20 0.44
RECQL P46063 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
ELANE P08246 1/20 0.41
LMNA P02545 3/20 0.40
GAA P10253 2/20 0.40
ACHE P22303 1/20 0.39
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 1/20 0.37
KCNA5 P22460 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
HTT P42858 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
PTGES O14684 1/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 1/20 0.36
PKM P14618 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7722372 0.94 KMT2A (0.49) KMT2AESR1HIF1ARECQLSMN1; SMN2
SCHEMBL7720645 0.89 KMT2A (0.41) KMT2AESR1HIF1ARECQLSMN1; SMN2
SCHEMBL7724577 0.89 ELANE (0.51) KMT2AESR1HIF1ARECQLSMN1; SMN2
SCHEMBL7720748 0.86 KMT2A (0.41) KMT2AESR1HIF1ARECQLSMN1; SMN2
SCHEMBL7721784 0.86 KMT2A (0.41) KMT2AESR1HIF1ARECQLSMN1; SMN2
SCHEMBL7717473 0.85 KMT2A (0.43) KMT2AESR1HIF1ARECQLSMN1; SMN2
SCHEMBL7720737 0.85 LMNA (0.59) KMT2ASMN1; SMN2ELANELMNAGAA
SCHEMBL7722368 0.84 KMT2A (0.49) KMT2AESR1HIF1ARECQLSMN1; SMN2
SCHEMBL7722375 0.83 BCL9 (0.51) KMT2AESR1HIF1ARECQLSMN1; SMN2
SCHEMBL7724559 0.82 PRSS1 (0.48) KMT2ASMN1; SMN2GAAMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6395446-B1 CONTAINING SULFONYLDIAZOMETHANE COMPOUND AS ACID GENERATOR SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-05-28 US disclosed