Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7722372 | 0.94 | KMT2A (0.49) | ELANEKMT2AESR1HIF1ASMN1; SMN2 | |
| SCHEMBL7724562 | 0.89 | KMT2A (0.51) | ELANEKMT2AESR1HIF1ASMN1; SMN2 | |
| SCHEMBL7720748 | 0.86 | KMT2A (0.41) | ELANEKMT2AESR1HIF1ASMN1; SMN2 | |
| SCHEMBL7721784 | 0.86 | KMT2A (0.41) | ELANEKMT2AESR1HIF1ASMN1; SMN2 | |
| SCHEMBL7717473 | 0.85 | KMT2A (0.43) | ELANEKMT2AESR1HIF1ASMN1; SMN2 | |
| SCHEMBL7722416 | 0.85 | MAPT (0.54) | ELANEKMT2ASMN1; SMN2LMNAPTGS2 | |
| SCHEMBL7722375 | 0.83 | BCL9 (0.51) | ELANEKMT2AESR1HIF1ASMN1; SMN2 | |
| SCHEMBL7721805 | 0.82 | ELANE (0.53) | ELANEKMT2AESR1HIF1ASMN1; SMN2 | |
| SCHEMBL7720645 | 0.82 | KMT2A (0.41) | ELANEKMT2AESR1HIF1ASMN1; SMN2 | |
| SCHEMBL7721775 | 0.81 | ELANE (0.51) | ELANESMN1; SMN2LMNAPTGS2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395446-B1 | CONTAINING SULFONYLDIAZOMETHANE COMPOUND AS ACID GENERATOR | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |