Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095464 | 0.99 | ALDH1A1 (0.33) | ALDH1A1ALOX15HSD17B10HPGDAPOBEC3G | |
| Hydrochloric Acid SCHEMBL7718297 | 0.84 | — | — | |
| SCHEMBL8104847 | 0.83 | TSHR (0.30) | TSHR | |
| Hydrochloric Acid SCHEMBL7718850 | 0.82 | — | — | |
| SCHEMBL8109098 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL7718845 | 0.77 | PRSS1 (0.34) | ALDH1A1HPGDKDM4EGAAMAPT | |
| Hydrochloric Acid SCHEMBL7713852 | 0.76 | PRSS1 (0.35) | — | |
| SCHEMBL8104786 | 0.76 | PRSS1 (0.35) | ALDH1A1HSD17B10HPGDKDM4EGAA | |
| Hydrochloric Acid SCHEMBL7717328 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL7672524 | 0.74 | KMT2A (0.33) | ALDH1A1HSD17B10HPGDKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6383230-B1 | COLORFASTNESS, PHOTOSTABILITY, WATERPROOFING, WEATHERPROOFING | L'OREAL (FR) | 2002-05-07 | — | — | US | claimed |
| US-6383230-B1 | COLORFASTNESS, PHOTOSTABILITY, WATERPROOFING, WEATHERPROOFING | L'OREAL (FR) | 2002-05-07 | — | — | US | disclosed |