Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9725963 | 0.81 | ALDH1A1 (0.67) | ALDH1A1NPSR1CYP3A4MAPTCYP2C19 | |
| SCHEMBL7721150 | 0.81 | LMNA (0.51) | ALDH1A1NPSR1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL7721157 | 0.78 | SMN1; SMN2 (0.47) | ALDH1A1TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL13768080 | 0.76 | ALDH1A1 (0.63) | ALDH1A1NPSR1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL7726932 | 0.76 | HSD17B10 (0.53) | ALDH1A1TSHRMAPTSMN1; SMN2MEN1 | |
| SCHEMBL7721559 | 0.75 | SMN1; SMN2 (0.53) | ALDH1A1TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL14256501 | 0.70 | POLB (0.53) | ALDH1A1TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL13610834 | 0.70 | ALDH1A1 (0.59) | ALDH1A1NPSR1TSHRCYP1A2CYP3A4 | |
| SCHEMBL4476411 | 0.70 | ALDH1A1 (0.71) | ALDH1A1NPSR1CYP3A4MAPTCYP2C19 | |
| SCHEMBL19079880 | 0.69 | USP2 (0.82) | ALDH1A1TSHRSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6875765-B2 | Arylsulfonamide ethers, and methods of use thereof | WARNER-LAMBERT COMPANY (US) | 2005-04-05 | — | — | US | disclosed |