SCHEMBL7721178

SCHEMBL7721178

CCCCCCCCc1ccccc1OC1CO1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
THRA P10827 2/20 0.48
THRB P10828 2/20 0.48
PPARA Q07869 2/20 0.46
LIPG Q9Y5X9 1/20 0.45
PTGS2 P35354 2/20 0.44
ALOX5 P09917 1/20 0.44
PPARG P37231 1/20 0.44
NR1H2 P55055 1/20 0.38
NR1H3 Q13133 1/20 0.38
CYSLTR2 Q9NS75 3/20 0.38
CYSLTR1 Q9Y271 3/20 0.38
LTB4R Q15722 1/20 0.36
LTB4R2 Q9NPC1 1/20 0.36
ELANE P08246 1/20 0.36
BID P55957 2/20 0.36
BCL2L1 Q07817 2/20 0.36
MCL1 Q07820 2/20 0.36
BAK1 Q16611 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8596519 1.00 THRA (0.48) THRATHRBPPARALIPGPTGS2
Alcohol SCHEMBL8073596 0.97 THRA (0.49) THRATHRBPPARALIPGPTGS2
Methyl Alcohol SCHEMBL11123436 0.97 THRA (0.49) THRATHRBPPARALIPGPTGS2
SCHEMBL7774653 0.84 THRA (0.42) THRATHRBPPARALIPGPTGS2
SCHEMBL7233664 0.84 THRA (0.42) THRATHRBPPARALIPGPTGS2
SCHEMBL7784057 0.82 THRA (0.43) THRATHRBPPARALIPGPTGS2
SCHEMBL7783124 0.82 THRA (0.43) THRATHRBPPARALIPGPTGS2
SCHEMBL457984 0.79 ALDH1A1 (0.56) THRATHRBPPARALIPGPTGS2
SCHEMBL283478 0.79 ALDH1A1 (0.56) THRATHRBPPARALIPGPTGS2
SCHEMBL283615 0.79 ALDH1A1 (0.56) THRATHRBPPARALIPGPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1822858-A Stable non-dihydrate azithromycin oral suspensions PFIZER PROD INC (US) 2006-08-23 CN disclosed
US-6381918-B2 Wallboard adhesive ILLINOIS TOOL WORKS INC. 2002-05-07 US disclosed
US-20010054482-A1 Wallboard adhesive ILLINOIS TOOL WORKS, INC. 2001-12-27 US disclosed
US-6300400-B1 OPEN TIME AND GREEN STRENGTH CHARACTERISTICS ILLINOIS TOOL WORKS INC. 2001-10-09 US disclosed
EP-0597567-B1 Process of preparing large dimension emulsion polymer particles, polymer product and uses thereof ROHM & HAAS (US) 1999-08-18 EP disclosed
US-5369163-A Process for preparing large dimension emulsion polymer particles, polymer product and uses thereof ROHM AND HAAS COMPANY (US) 1994-11-29 US disclosed