Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.39 |
| ▸ | BID | P55957 | 3/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.38 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.38 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL11123436 | 0.97 | THRA (0.49) | THRATHRBPPARALIPGALOX5 | |
| SCHEMBL8596519 | 0.97 | THRA (0.48) | THRATHRBPPARALIPGALOX5 | |
| SCHEMBL7721178 | 0.97 | THRA (0.48) | THRATHRBPPARALIPGALOX5 | |
| SCHEMBL7774653 | 0.81 | THRA (0.42) | THRATHRBPPARALIPGALOX5 | |
| SCHEMBL7233664 | 0.81 | THRA (0.42) | THRATHRBPPARALIPGALOX5 | |
| SCHEMBL7783124 | 0.80 | THRA (0.43) | THRATHRBPPARALIPGALOX5 | |
| SCHEMBL7784057 | 0.80 | THRA (0.43) | THRATHRBPPARALIPGALOX5 | |
| SCHEMBL457984 | 0.77 | ALDH1A1 (0.56) | THRATHRBPPARALIPGALOX5 | |
| SCHEMBL283615 | 0.77 | ALDH1A1 (0.56) | THRATHRBPPARALIPGALOX5 | |
| SCHEMBL4615425 | 0.77 | ALDH1A1 (0.56) | THRATHRBPPARALIPGALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4777112-A | THE POLYETHER HYDROGEN-BONDED TO ANOTHER POLYMER AND SALT OF POLYVINYLHYDROGEN PHTHALATE | POLAROID CORPORATION (US) | 1988-10-11 | — | — | US | claimed |
| EP-0027461-A4 | COLOR TRANSFER FILM AND PROCESS. | POLAROID CORP (US) | 1982-07-12 | — | — | EP | claimed |
| US-4298674-A | WHEREIN PROCESSING COMPOSITION INCLUDES LIGHT-REFLECTING PIGMENT AND PH-SENSITIVE OPTICAL FILTER | POLAROID CORPORATION (US) | 1981-11-03 | — | — | US | claimed |
| EP-0027461-A1 | COLOR TRANSFER FILM AND PROCESS. | POLAROID CORP (US) | 1981-04-29 | — | — | EP | claimed |
| WO-1980002333-A1 | COLOR TRANSFER FILM AND PROCESS | POLAROID CORP (US) | 1980-10-30 | — | — | WO | claimed |
| US-6103912-A | OPTICAL INFRARED FILTERS COMPRISING PH SENSITIVE DYES | POLAROID CORPORATION (US) | 2000-08-15 | — | — | US | disclosed |
| EP-0823068-B1 | COLOR-PROVIDING COMPOUNDS | POLAROID CORP (US) | 2000-08-09 | — | — | EP | disclosed |
| EP-0683430-B1 | Photographic processing compositions including hydrophobically modified thickening agent | POLAROID CORP (US) | 1999-03-31 | — | — | EP | disclosed |
| EP-0553346-B1 | PHOTOGRAPHIC PRODUCTS AND PROCESSES | POLAROID CORP (US) | 1998-01-28 | — | — | EP | disclosed |
| US-5658705-A | HEAT DEVELOPABLE | POLAROID CORPORATION (US) | 1997-08-19 | — | — | US | disclosed |
| EP-0683430-A2 | Photographic processing compositions including hydrophobically modified thickening agent | POLAROID CORPORATION (US) | 1995-11-22 | — | — | EP | disclosed |
| US-5422233-A | Based on a copolymer of an acrylic acid and an acrylic ester or amide in an aqueous alkali solution of pH 10+; self-development/photo/; diffusion transfer; nonpooling; nonhydrolyzing; nonseparating | POLAROID CORPORATION (US) | 1995-06-06 | — | — | US | disclosed |
| US-4503138-A | DIFFUSION TRANSFER | POLAROID CORPORATION (US) | 1985-03-05 | — | — | US | disclosed |
| EP-0027461-A4 | COLOR TRANSFER FILM AND PROCESS. | POLAROID CORP (US) | 1982-07-12 | — | — | EP | disclosed |
| US-4298674-A | WHEREIN PROCESSING COMPOSITION INCLUDES LIGHT-REFLECTING PIGMENT AND PH-SENSITIVE OPTICAL FILTER | POLAROID CORPORATION (US) | 1981-11-03 | — | — | US | disclosed |
| US-4294907-A | DIFFUSION TRANSFER FILMS | POLAROID CORPORATION (US) | 1981-10-13 | — | — | US | disclosed |
| EP-0027461-A1 | COLOR TRANSFER FILM AND PROCESS. | POLAROID CORP (US) | 1981-04-29 | — | — | EP | disclosed |
| US-4264507-A | Novel xanthene dye developers | POLAROID CORPORATION (US) | 1981-04-28 | — | — | US | disclosed |
| US-4264704-A | Novel xanthene dye developers | POLAROID CORPORATION (US) | 1981-04-28 | — | — | US | disclosed |
| WO-1980002333-A1 | COLOR TRANSFER FILM AND PROCESS | POLAROID CORP (US) | 1980-10-30 | — | — | WO | disclosed |