Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | PTPRB | P23467 | 2/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | PTPRG | P23470 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PTPRA | P18433 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7722455 | 0.85 | ALDH1A1 (0.39) | CA12CA7CA14CA9PTPN2 | |
| SCHEMBL5674360 | 0.83 | CES1 (0.39) | CA12CA7CA14CA9PTPN2 | |
| SCHEMBL8165047 | 0.73 | ALDH1A1 (0.47) | MEN1KMT2ARIPK1ALDH1A1KDM4E | |
| SCHEMBL11011925 | 0.72 | GRM2 (0.40) | CA12CA9CA1RIPK1KDM4E | |
| SCHEMBL1434444 | 0.70 | KMT2A (0.45) | MEN1KMT2A | |
| SCHEMBL11016084 | 0.70 | CTBP2 (0.42) | ALDH1A1 | |
| SCHEMBL585945 | 0.70 | ALDH1A1 (0.47) | MEN1KMT2ARIPK1ALDH1A1KDM4E | |
| SCHEMBL18085386 | 0.70 | ALDH1A1 (0.47) | MEN1KMT2ARIPK1ALDH1A1KDM4E | |
| SCHEMBL17726949 | 0.69 | ALDH1A1 (0.47) | MEN1KMT2ARIPK1ALDH1A1KDM4E | |
| SCHEMBL7713930 | 0.69 | MMP8 (0.58) | MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395918-B1 | Conversion of a hydroxy group in certain alcohols into a fluorosulfonate ester or a trifluoromethylsulfonate ester | LOEWENTHAL HANS JACOB EDGAR (IL) | 2002-05-28 | — | — | US | disclosed |