Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 7/20 | 0.44 |
| ▸ | PPARD | Q03181 | 4/20 | 0.44 |
| ▸ | PPARG | P37231 | 6/20 | 0.42 |
| ▸ | GPR183 | P32249 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1434771 | 0.80 | KDM4E (0.60) | KMT2AMEN1POLBPPARAPPARD | |
| SCHEMBL23754112 | 0.77 | PPARG (0.45) | KMT2AMEN1PPARAPPARDPPARG | |
| SCHEMBL8417757 | 0.76 | PPARA (0.40) | KMT2AMEN1PPARAPPARDPPARG | |
| SCHEMBL11763480 | 0.75 | PPARG (0.44) | KMT2AMEN1PPARAPPARDPPARG | |
| SCHEMBL27597559 | 0.74 | PPARG (0.47) | PPARAPPARDPPARG | |
| SCHEMBL28212657 | 0.74 | GAA (0.44) | KMT2APPARAPPARDPPARG | |
| SCHEMBL7722455 | 0.72 | ALDH1A1 (0.39) | — | |
| SCHEMBL7862961 | 0.72 | PPARA (0.44) | PPARAPPARDPPARG | |
| SCHEMBL10872140 | 0.72 | LMNA (0.45) | KMT2AMEN1POLBPPARAPPARD | |
| SCHEMBL8165047 | 0.72 | ALDH1A1 (0.47) | KMT2AMEN1POLBFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1742927-B1 | BUTANOIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM, AND THERAPEUTIC APPLICATIONS THREREOF | MERCK PATENT GMBH (DE) | 2011-03-30 | — | — | EP | disclosed |