Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | ATM | Q13315 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NOS1 | P29475 | 3/20 | 0.37 |
| ▸ | NOS2 | P35228 | 3/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11059805 | 0.90 | MEN1 (0.41) | L3MBTL1ATMALDH1A1GAAGLA | |
| SCHEMBL907974 | 0.82 | PRKCZ (0.41) | PRKCZ | |
| SCHEMBL7719321 | 0.82 | PRKCZ (0.40) | L3MBTL1ATMALDH1A1GAAGLA | |
| Hydrochloric Acid SCHEMBL10656738 | 0.81 | PRKCZ (0.40) | PRKCZ | |
| SCHEMBL907869 | 0.80 | PRKCZ (0.45) | L3MBTL1PRKCZMEN1KMT2AALOX5 | |
| SCHEMBL908054 | 0.80 | PRKCZ (0.45) | ALDH1A1GAAKDM4ESMN1; SMN2PRKCZ | |
| SCHEMBL13387492 | 0.79 | MAPT (0.47) | L3MBTL1ATMALDH1A1GAAGLA | |
| SCHEMBL16139718 | 0.78 | MEN1 (0.36) | L3MBTL1ATMALDH1A1GAAGLA | |
| SCHEMBL11068412 | 0.78 | MEN1 (0.54) | L3MBTL1ATMALDH1A1GAAGLA | |
| SCHEMBL7719090 | 0.77 | PRKCZ (0.35) | L3MBTL1ATMALDH1A1GAAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387136-B1 | OXIDATION COLOR DYES AND COUPLER | L'OREAL S.A. (FR) | 2002-05-14 | — | — | US | claimed |
| EP-0974337-B1 | Keratinous fibre dyeing compositions containing 3-amino pyrazoline derivatives as coupling agents, process for dyeing and dyeing kit | OREAL (FR) | 2001-03-21 | — | — | EP | claimed |
| EP-0974337-A1 | Keratinous fibre dyeing compositions containing 3-amino pyrazoline derivatives as coupling agents, process for dyeing and dyeing kit | L'OREAL (FR) | 2000-01-26 | — | — | EP | claimed |
| US-6387136-B1 | OXIDATION COLOR DYES AND COUPLER | L'OREAL S.A. (FR) | 2002-05-14 | — | — | US | disclosed |
| EP-0974337-B1 | Keratinous fibre dyeing compositions containing 3-amino pyrazoline derivatives as coupling agents, process for dyeing and dyeing kit | OREAL (FR) | 2001-03-21 | — | — | EP | disclosed |
| EP-0974337-A1 | Keratinous fibre dyeing compositions containing 3-amino pyrazoline derivatives as coupling agents, process for dyeing and dyeing kit | L'OREAL (FR) | 2000-01-26 | — | — | EP | disclosed |
| EP-0022578-B1 | PHARMACEUTICAL COMPOSITIONS CONTAINING 3-AMINO-PYRAZOLINE DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1988-06-29 | — | — | EP | disclosed |
| EP-0055418-B1 | PYRAZOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | THE WELLCOME FOUNDATION LIMITED (GB) | 1986-02-26 | — | — | EP | disclosed |
| US-4564684-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIBODY INHIBITORY | COPP FREDERICK C (GB) | 1986-01-14 | — | — | US | disclosed |
| US-4556671-A | Pharmaceutical formulations | BURROUGHS WELLCOME CO. (US) | 1985-12-03 | — | — | US | disclosed |
| US-4447442-A | ANTIINFLAMMATORY, ANTIARTHRITIC, ANTIHISTAMINE, ANTIALLERGENS, ANALGESICS, BACTERICIDES, AND FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4432991-A | ANALGESICS, FUNGICIDE, BACTERICIDE, ANTIINFLAMMATORY, OR ANTIARTHRITIC AGENTS, ANTIALLERGENS, AND BRONCHODILATOR | AMERICAN CYANAMID COMPANY (US) | 1984-02-21 | — | — | US | disclosed |
| EP-0070376-A1 | Heterocyclic substituted-amino-pyrazolines | AMERICAN CYANAMID COMPANY (US) | 1983-01-26 | — | — | EP | disclosed |
| US-4360680-A | ANALGESIC, ANTIINFLAMMATORY AGENT, FUNGICIDE AND BACTERICIDE | AMERICAN CYANAMID COMPANY (US) | 1982-11-23 | — | — | US | disclosed |
| US-4348527-A | ANALGESICS, BACTERICIDES, FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1982-09-07 | — | — | US | disclosed |
| EP-0055418-A2 | Pyrazoline derivatives, processes for their preparation and pharmaceutical formulations containing them | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-07-07 | — | — | EP | disclosed |
| US-4268436-A | OXIDATIVE DIAZOTIZATION WITH NITROSYLSULFURIC ACID, ALKALINE METAL NITRITES, OR ALKYL NITRITES | AZIENDE COLORI NAZIONALI AFFINI ACNA S.P.A. (IT) | 1981-05-19 | — | — | US | disclosed |
| EP-0022578-A1 | Pharmaceutical compositions containing 3-Amino-pyrazoline derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1981-01-21 | — | — | EP | disclosed |
| EP-0011295-A1 | Yellow monoazo dyes of the 2-hydroxydibenzofuran series; their preparation and use for dyeing and printing synthetic hydrophobic fibres | Montedison S.p.A. (IT) | 1980-05-28 | — | — | EP | disclosed |