Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.36 |
| ▸ | ATM | Q13315 | 5/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | GLA | P06280 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.35 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7721905 | 0.78 | L3MBTL1 (0.40) | MEN1KMT2AATMHSP90AA1L3MBTL1 | |
| SCHEMBL11068412 | 0.78 | MEN1 (0.54) | MEN1KMT2AATMHSP90AA1L3MBTL1 | |
| SCHEMBL16139671 | 0.76 | MEN1 (0.40) | MEN1KMT2AKDM4EMAPTMAPK1 | |
| SCHEMBL7714597 | 0.75 | DPP4 (0.37) | MEN1KMT2AATMGLAMAPT | |
| SCHEMBL7719090 | 0.74 | PRKCZ (0.35) | MEN1KMT2AATMHSP90AA1L3MBTL1 | |
| SCHEMBL7717975 | 0.74 | ALDH1A1 (0.39) | MEN1KMT2AATMHSP90AA1L3MBTL1 | |
| SCHEMBL1781467 | 0.74 | NOS1 (0.39) | MEN1KMT2AATMHSP90AA1L3MBTL1 | |
| SCHEMBL10418491 | 0.71 | MEN1 (0.57) | MEN1KMT2AATML3MBTL1KDM4E | |
| SCHEMBL11060055 | 0.71 | EGFR (0.53) | MEN1KMT2AATMHSP90AA1L3MBTL1 | |
| SCHEMBL11060811 | 0.71 | PRKCZ (0.56) | MEN1KMT2AATMEGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2784074-A1 | PYRAZOLE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | Japan Tobacco, Inc. (JP) | 2014-10-01 | — | — | EP | disclosed |