SCHEMBL7722083

SCHEMBL7722083

COc1ccc([B-](c2ccc(OC)c(OC)c2)(c2ccc(OC)c(OC)c2)c2ccc(OC)c(OC)c2)cc1OC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.52
CA12 O43570 3/20 0.52
CA1 P00915 3/20 0.52
CA7 P43166 3/20 0.52
CA9 Q16790 3/20 0.52
CA14 Q9ULX7 3/20 0.52
ACHE P22303 1/20 0.52
TSHR P16473 3/20 0.45
CYP1A2 P05177 2/20 0.45
ALDH1A1 P00352 2/20 0.45
POLB P06746 2/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
MAPK1 P28482 1/20 0.45
CA4 P22748 2/20 0.43
PDE4A P27815 1/20 0.43
NR3C1 P04150 1/20 0.43
CA6 P23280 1/20 0.43
TPMT P51580 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Potassium Ion SCHEMBL15921079 0.79 CA2 (0.46) CA2CA12CA1CA7CA9
SCHEMBL4532734 0.74 CYP3A4 (0.53) CA2CA12CA1CA7CA9
SCHEMBL13518528 0.74 CYP3A4 (0.53) CA2CA12CA1CA7CA9
SCHEMBL8840880 0.70 PDE4A (0.67) CA2CA12CA1CA7CA9
SCHEMBL29403877 0.69 ACHE (1.00) CA2CA12CA1CA7CA9
1,2,4-Trimethoxybenzene SCHEMBL29350371 0.69 CA12 (1.00) CA2CA12CA1CA7CA9
SCHEMBL1402508 0.69 CA2 (0.56) CA2CA12CA1CA7CA9
1,2,4-Trimethoxybenzene SCHEMBL481491 0.69 CA12 (1.00) CA2CA12CA1CA7CA9
SCHEMBL12518 0.69 ACHE (1.00) CA2CA12CA1CA7CA9
1,2,4-Trimethoxybenzene SCHEMBL27777905 0.69 CA12 (1.00) CA2CA12CA1CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6387975-B1 ORGANOMETALLIC COMPOUND COMPLEX AUTEX, INC. (JP) 2002-05-14 US claimed
US-6387975-B1 ORGANOMETALLIC COMPOUND COMPLEX AUTEX, INC. (JP) 2002-05-14 US disclosed