Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7722389 | 0.91 | ELANE (0.50) | ELANEMAPTTDP1KMT2APOLB | |
| SCHEMBL7720716 | 0.88 | MAPT (0.50) | ELANEMAPTTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL7721700 | 0.88 | ELANE (0.42) | ELANEMAPTTDP1L3MBTL1POLB | |
| SCHEMBL7722388 | 0.87 | ELANE (0.44) | ELANEMAPTTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL7721775 | 0.86 | ELANE (0.51) | ELANEMAPTTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL7724552 | 0.86 | ELANE (0.45) | ELANEMAPTTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL7724572 | 0.85 | ELANE (0.44) | ELANEMAPTTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL7717464 | 0.84 | ELANE (0.46) | ELANEMAPTTDP1KMT2APOLB | |
| SCHEMBL7721784 | 0.82 | KMT2A (0.41) | ELANEMAPTTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL383925 | 0.82 | ALDH1A1 (0.50) | MAPTTDP1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395446-B1 | CONTAINING SULFONYLDIAZOMETHANE COMPOUND AS ACID GENERATOR | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |