Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7722389 | 0.94 | ELANE (0.50) | ELANELMNAKMT2ATDP1PKM | |
| SCHEMBL7721775 | 0.89 | ELANE (0.51) | ELANELMNATDP1ALDH1A1PKM | |
| SCHEMBL7721774 | 0.88 | ELANE (0.38) | ELANELMNAKMT2ATDP1ALDH1A1 | |
| SCHEMBL7717464 | 0.88 | ELANE (0.46) | ELANEKMT2ATDP1PKMPOLB | |
| SCHEMBL7720737 | 0.87 | LMNA (0.59) | ELANELMNAKMT2AALDH1A1PKM | |
| SCHEMBL7721700 | 0.86 | ELANE (0.42) | ELANETDP1PKMPOLBMAPT | |
| SCHEMBL7722348 | 0.86 | ELANE (0.42) | ELANEKMT2ATDP1ALDH1A1PKM | |
| SCHEMBL7722388 | 0.85 | ELANE (0.44) | ELANETDP1ALDH1A1PKMPOLB | |
| SCHEMBL7724582 | 0.84 | ELANE (0.47) | ELANELMNAKMT2ATDP1ALDH1A1 | |
| SCHEMBL7724559 | 0.82 | PRSS1 (0.48) | KMT2AMAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395446-B1 | CONTAINING SULFONYLDIAZOMETHANE COMPOUND AS ACID GENERATOR | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |