Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 8/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PRTN3 | P24158 | 3/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7722389 | 0.90 | ELANE (0.50) | ELANEPOLBMAPTPKMTDP1 | |
| SCHEMBL7717451 | 0.88 | MAPT (0.53) | ELANEPOLBMAPTPKMTDP1 | |
| SCHEMBL7721700 | 0.87 | ELANE (0.42) | ELANEPOLBMAPTPKMTDP1 | |
| SCHEMBL7722348 | 0.87 | ELANE (0.42) | ELANEPOLBMAPTPKMTDP1 | |
| SCHEMBL7717464 | 0.86 | ELANE (0.46) | ELANEPOLBMAPTPKMTDP1 | |
| SCHEMBL7724552 | 0.85 | ELANE (0.45) | ELANEPOLBMAPTPKMTDP1 | |
| SCHEMBL7721775 | 0.85 | ELANE (0.51) | ELANEPOLBMAPTPKMTDP1 | |
| SCHEMBL7717473 | 0.82 | KMT2A (0.43) | ELANEPOLBMAPTPKMSMN1; SMN2 | |
| SCHEMBL7722363 | 0.81 | ELANE (0.43) | ELANEPOLBMAPTPKMTDP1 | |
| SCHEMBL7721774 | 0.80 | ELANE (0.38) | ELANEPOLBMAPTPKMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395446-B1 | CONTAINING SULFONYLDIAZOMETHANE COMPOUND AS ACID GENERATOR | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |