Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13444378 | 0.81 | — | — | |
| SCHEMBL10331063 | 0.78 | — | — | |
| SCHEMBL13444359 | 0.78 | — | — | |
| SCHEMBL17052683 | 0.74 | KDM4E (0.34) | KDM4EALDH1A1GAAMAPK1 | |
| SCHEMBL13444385 | 0.73 | — | — | |
| SCHEMBL18748208 | 0.73 | — | — | |
| SCHEMBL14791120 | 0.72 | — | — | |
| SCHEMBL18213892 | 0.71 | — | — | |
| SCHEMBL13444377 | 0.70 | — | — | |
| SCHEMBL13297910 | 0.69 | KDM4E (0.46) | KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230277547-A1 | SUBSTITUTED QUINOXALINE DNA-PK INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-09-07 | — | — | US | disclosed |
| US-11731977-B2 | SGC stimulators | CYCLERION THERAPEUTICS, INC. (US) | 2023-08-22 | — | — | US | disclosed |
| US-11698480-B2 | Optical product and optical filter including same | LMS CO., LTD. (KR) | 2023-07-11 | — | — | US | disclosed |
| US-20230128639-A1 | PROCESS FOR PREPARING SOLUBLE GUANYLATE CYCLASE STIMULATORS | TISENTO THERAPEUTICS INC. | 2023-04-27 | — | — | US | disclosed |
| US-10042209-B2 | Optical anisotropic film | LG CHEM, LTD. (KR) | 2018-08-07 | — | — | US | disclosed |
| US-20180208579-A1 | DNA-PK INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED | 2018-07-26 | — | — | US | disclosed |
| US-20180193341-A1 | DNA-PK INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED | 2018-07-12 | — | — | US | disclosed |
| US-20180161336-A1 | DNA-PK INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2018-06-14 | — | — | US | disclosed |
| US-20180155345-A1 | sGC STIMULATORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2018-06-07 | — | — | US | disclosed |
| US-9987284-B2 | Substituted benzooxadiazole DNA-PK inhibitors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2018-06-05 | — | — | US | disclosed |
| US-20090054402-A1 | 7-SUBSTITUTED INDOLE MCL-1 INHIBITORS | ABBOTT LABORATORIES (US) | 2009-02-26 | — | — | US | disclosed |
| US-20090045725-A1 | POLYARYLENE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-02-19 | — | — | US | disclosed |
| US-20080255111-A1 | Tissue Factor Production Inhibitor | SANKYO COMPANY LIMITED (JP) | 2008-10-16 | — | — | US | disclosed |
| US-20080061673-A1 | Solution Composition And Polymer Light-Emitting Device | SUMITOMO CHEMICAL CO., LTD. (JP) | 2008-03-13 | — | — | US | disclosed |
| US-20070207995-A1 | Deazapurines useful as inhibitors of Janus kinases | VERTEX PHARMACEUTICALS INCORPORATED | 2007-09-06 | — | — | US | disclosed |
| US-20070203142-A1 | for treating proliferative disorders, cardiac disorders, neurodegenerative disorders, autoimmune disorders, conditions associated with organ transplantation, inflammatory disorders, and/or immunologically mediated disorders | VERTEX PHARMACEUTICALS INCORPORATED | 2007-08-30 | — | — | US | disclosed |
| US-20070158214-A1 | Electrochemical method and system for detection of trace explosives | MEDIS TECHNOLOGIES LTD. (IL) | 2007-07-12 | — | — | US | disclosed |
| US-20070131566-A1 | Electrochemical method and system for detection of trace explosives | MEDIS TECHNOLOGIES LTD. (IL) | 2007-06-14 | — | — | US | disclosed |
| US-20070099909-A1 | N-(2-ARYLETHYL)BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR | CHEN ZHAOGEN | 2007-05-03 | — | — | US | disclosed |
| US-7157488-B2 | N-(2-Arylethyl) benzylamines as antagonists of the 5-HT6 receptor | ELI LILLY AND COMPANY (US) | 2007-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230277547-A1 | SUBSTITUTED QUINOXALINE DNA-PK INHIBITORS | DTYMK, POLK, TOP1 | KDM4E 569/4885ALDH1A1 2519/4885GAA 180/4885 |
| US-20080255111-A1 | Tissue Factor Production Inhibitor | PTAFR, PLAT, TFPI | KDM4E 4805/4885ALDH1A1 4330/4885GAA 1101/4885 |
| US-20070203142-A1 | for treating proliferative disorders, cardiac disorders, neurodegenerative disorders, autoimmune disorders, conditions associated with organ transplantation, inflammatory disorders, and/or immunologically mediated disorders | JAK1, JAK3, MYLK2 | KDM4E 2438/4885ALDH1A1 3464/4885GAA 1356/4885 |
| US-20230128639-A1 | PROCESS FOR PREPARING SOLUBLE GUANYLATE CYCLASE STIMULATORS | GUCY1A2, GUCY1B2, GUCY1A1 | KDM4E 2005/4885ALDH1A1 3061/4885GAA 1954/4885 |
| US-20180193341-A1 | DNA-PK INHIBITORS | POLK, DTYMK, DCK | KDM4E 910/4885ALDH1A1 2935/4885GAA 234/4885 |
| US-20180161336-A1 | DNA-PK INHIBITORS | POLK, DTYMK, DCK | KDM4E 910/4885ALDH1A1 2935/4885GAA 234/4885 |
| US-20180208579-A1 | DNA-PK INHIBITORS | POLK, DTYMK, DCK | KDM4E 910/4885ALDH1A1 2935/4885GAA 234/4885 |
| US-20070207995-A1 | Deazapurines useful as inhibitors of Janus kinases | JAK1, JAK3, JAK2 | KDM4E 544/4885ALDH1A1 2028/4885GAA 1749/4885 |
| US-11731977-B2 | SGC stimulators | GUCY1A2, PRKG1, GMPS | KDM4E 3250/4885ALDH1A1 2650/4885GAA 250/4885 |
| US-20070099909-A1 | N-(2-ARYLETHYL)BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR | HTR6, HTR2C, HTR1B | KDM4E 1970/4885ALDH1A1 1218/4885GAA 4200/4885 |
| US-20090054402-A1 | 7-SUBSTITUTED INDOLE MCL-1 INHIBITORS | MCL1, BCL2L1, API5 | KDM4E 2331/4885ALDH1A1 2525/4885GAA 3296/4885 |
| US-20180155345-A1 | sGC STIMULATORS | GUCY1B1, GUCY1A1, PRKG1 | KDM4E 911/4885ALDH1A1 1902/4885GAA 2776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.