Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.39 |
| ▸ | RARA | P10276 | 2/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 3/20 | 0.33 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7729545 | 0.97 | RARB (0.43) | RARBRARARARGS1PR1S1PR3 | |
| SCHEMBL7722493 | 0.94 | S1PR1 (0.36) | RARBRARARARGS1PR1CETP | |
| SCHEMBL7722798 | 0.93 | S1PR1 (0.37) | S1PR1S1PR3PSEN1CETPCACNA1H | |
| SCHEMBL7730764 | 0.92 | S1PR1 (0.38) | S1PR1S1PR3PSEN1CETPCACNA1H | |
| SCHEMBL7735808 | 0.91 | S1PR1 (0.40) | S1PR1S1PR3PSEN1CETPCACNA1H | |
| SCHEMBL7732575 | 0.90 | S1PR1 (0.35) | RARBRARARARGS1PR1S1PR3 | |
| SCHEMBL7731626 | 0.89 | CYP17A1 (0.36) | S1PR1CACNA1HCYP17A1PPARD | |
| SCHEMBL7730786 | 0.89 | HTR2A (0.35) | RARBRARARARGS1PR1S1PR3 | |
| SCHEMBL7733331 | 0.88 | S1PR1 (0.38) | S1PR1S1PR3PSEN1CACNA1HPPARG | |
| SCHEMBL7729471 | 0.88 | RARB (0.37) | RARBRARARARGS1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |
| EP-0786445-A1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1997-07-30 | — | — | EP | disclosed |