Dibenzothiophene

Dibenzothiophene

SCHEMBL7722649

Oc1ccc2sc3ccccc3c2c1O.c1ccc2c(c1)sc1ccccc12

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.54
MAOA P21397 1/20 0.47
MAOB P27338 1/20 0.47
MAPT P10636 6/20 0.41
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
POLB P06746 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
ALOX5 P09917 1/20 0.41
DUSP3 P51452 1/20 0.41
BLM P54132 1/20 0.41
PTPN5 P54829 1/20 0.41
PTPN11 Q06124 1/20 0.41
MCL1 Q07820 1/20 0.41
CTDSP1 Q9GZU7 1/20 0.41
PTPN22 Q9Y2R2 1/20 0.41
RAB9A P51151 4/20 0.41
ALDH1A1 P00352 4/20 0.41
GAA P10253 3/20 0.41
KDM4E B2RXH2 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2932661 0.98 GPR3 (0.50) GPR3MAOAMAOBMAPTMEN1
SCHEMBL29945065 0.98 GPR3 (0.50) GPR3MAOAMAOBMAPTMEN1
SCHEMBL9785865 0.84 MAOA (0.64) GPR3MAOAMAOBMAPTMEN1
SCHEMBL3872864 0.79 GPR3 (0.46) GPR3MAOAMAOBMAPTMEN1
SCHEMBL3885467 0.79 GPR3 (0.46) GPR3MAOAMAOBMAPTMEN1
SCHEMBL24519122 0.79 GPR3 (0.46) GPR3MAOAMAOBMAPTMEN1
SCHEMBL3882633 0.79 PIM1 (0.43) MAOAMAOBMAPTPOLBTDP1
SCHEMBL1636538 0.79 GPR3 (0.68) GPR3MAOAMAOBMAPTMEN1
SCHEMBL2338956 0.78 GPR3 (0.54) GPR3MAOAMAOBMAPTMEN1
SCHEMBL25007867 0.75 LIMK1 (0.46) GPR3MAOAMAOBMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0821982-B1 High-Temperature Desulfurization by Microorganisms JAPAN COOPERATION CT PETROLEUM (JP) 2002-05-02 EP disclosed
US-6130081-A MICROORGANISM WITH THE ABILITY TO DECOMPOSE ORGANIC SULFUR COMPOUNDS PETROLEUM ENERGY CENTER (JP) 2000-10-10 US disclosed
US-5925560-A CONTACTING ORGANIC SULFUR COMPOUNDS WITH PAENIBACILLUS; EFFICIENT CLEAVAGE OF C-S BONDS; POLLUTION CONTROL BY REMOVING SULFUR FROM PETROLEUM AND COAL PETROLEUM ENERGY CENTER (JP) 1999-07-20 US disclosed
EP-0821982-A2 High-Temperature Desulfurization by Microorganisms Petroleum Energy Center (JP) 1998-02-04 EP disclosed