SCHEMBL2932661

SCHEMBL2932661

Oc1ccc2sc3ccccc3c2c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.50
MAOA P21397 1/20 0.49
MAOB P27338 1/20 0.49
MAPT P10636 6/20 0.42
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
POLB P06746 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
DUSP3 P51452 1/20 0.42
BLM P54132 1/20 0.42
PTPN5 P54829 1/20 0.42
PTPN11 Q06124 1/20 0.42
MCL1 Q07820 1/20 0.42
CTDSP1 Q9GZU7 1/20 0.42
PTPN22 Q9Y2R2 1/20 0.42
RAB9A P51151 4/20 0.41
ALDH1A1 P00352 4/20 0.41
KDM4E B2RXH2 4/20 0.41
GAA P10253 3/20 0.41
MAPK1 P28482 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29945065 1.00 GPR3 (0.50) GPR3MAOAMAOBMAPTMEN1
Dibenzothiophene SCHEMBL7722649 0.98 GPR3 (0.54) GPR3MAOAMAOBMAPTMEN1
SCHEMBL9785865 0.85 MAOA (0.64) GPR3MAOAMAOBMAPTMEN1
SCHEMBL24519122 0.81 GPR3 (0.46) GPR3MAOAMAOBMAPTMEN1
SCHEMBL3872864 0.81 GPR3 (0.46) GPR3MAOAMAOBMAPTMEN1
SCHEMBL3885467 0.81 GPR3 (0.46) GPR3MAOAMAOBMAPTMEN1
SCHEMBL1636538 0.80 GPR3 (0.68) GPR3MAOAMAOBMAPTMEN1
SCHEMBL3882633 0.80 PIM1 (0.43) MAOAMAOBMAPTPOLBTDP1
SCHEMBL2338956 0.79 GPR3 (0.54) GPR3MAOAMAOBMAPTMEN1
SCHEMBL25007867 0.77 LIMK1 (0.46) GPR3MAOAMAOBMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7331997-B2 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof THE PROCTER & GAMBLE COMPANY (US) 2008-02-19 US claimed
US-20050217038-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof PROCTER & GAMBLE COMPANY, THE 2005-10-06 US claimed
CN-112458001-B Bacterial strain capable of degrading polycyclic aromatic hydrocarbon and application thereof 上海交通大学 2022-09-27 CN disclosed
CN-110662751-B Compound and color conversion film comprising same 株式会社LG化学 2022-07-19 CN disclosed
US-11091503-B2 Compound and color conversion film comprising the same LG CHEM, LTD. (KR) 2021-08-17 US disclosed
CN-112458001-A Bacterial strain capable of degrading polycyclic aromatic hydrocarbon and application thereof 上海交通大学 2021-03-09 CN disclosed
US-20200087324-A1 COMPOUND AND COLOR CONVERSION FILM COMPRISING THE SAME LG CHEM, LTD. (KR) 2020-03-19 US disclosed
CN-110662751-A Compound and color conversion film comprising same 株式会社LG化学 2020-01-07 CN disclosed
EP-3137299-A1 MULTILAYERED ARTICLES WITH LOW OPTICAL RETARDATION SABIC Global Technologies B.V. (NL) 2017-03-08 EP disclosed
CN-105899942-A Method for accelerated degradation of thermoplastics 沙特基础工业全球技术公司 2016-08-24 CN disclosed
CN-103224486-B S,S-dioxo-dibenzothiophene monomer containing polar substituent groups, water/alcohol soluble polymers thereof, and application thereof UNIV SOUTH CHINA TECH 2015-04-22 CN disclosed
US-7491245-B2 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof THE PROCTER & GAMBLE COMPANY (US) 2009-02-17 US disclosed
US-20080098535-A1 Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof GLENN ROBERT W JR 2008-05-01 US disclosed
US-7331997-B2 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof THE PROCTER & GAMBLE COMPANY (US) 2008-02-19 US disclosed
EP-1735059-A2 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF The Procter and Gamble Company (US) 2006-12-27 EP disclosed
WO-2005099656-A2 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF THE PROCTER & GAMBLE COMPANY (US) 2005-10-27 WO disclosed
US-20050217038-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof PROCTER & GAMBLE COMPANY, THE 2005-10-06 US disclosed
CN-1423637-A Novel substituted tricyclic compounds ASAHI CHEMICAL IND (JP) 2003-06-11 CN disclosed
US-4950731-A REACTING PHOSGENE WITH SPIROBIINDANE BISPHENOL IN HETEROGENEOUS BASE; ADDING INTERFACIAL POLYMERIZATION CATALYST GENERAL ELECTRIC COMPANY (US) 1990-08-21 US disclosed
US-3937835-A DELAYED HYPERSENSITIVITY RICHARDSON-MERRELL INC. (US) 1976-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050217038-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof KRT18, CKMT1A; CKMT1B, TUBB6 GPR3 4420/4885MAOA 500/4885MAOB 1005/4885
US-20200087324-A1 COMPOUND AND COLOR CONVERSION FILM COMPRISING THE SAME TRRAP, CDYL, MYB GPR3 4408/4885MAOA 122/4885MAOB 95/4885
US-20080098535-A1 Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof KRT18, CKMT1A; CKMT1B, TUBB6 GPR3 4420/4885MAOA 500/4885MAOB 1005/4885
US-11091503-B2 Compound and color conversion film comprising the same TRRAP, CDYL, MYB GPR3 4408/4885MAOA 122/4885MAOB 95/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.