Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL1651694 | 1.00 | CA2 (0.43) | CA2LMNASLC34A1FDPS | |
| Phosphoric Acid SCHEMBL29506218 | 1.00 | CA2 (0.43) | CA2LMNASLC34A1FDPS | |
| Propyne SCHEMBL7941983 | 0.85 | — | — | |
| Phosphoric Acid SCHEMBL28518252 | 0.84 | PGK1 (0.39) | CA2LMNAFDPS | |
| Phosphoric Acid SCHEMBL1654595 | 0.78 | CA2 (0.46) | CA2LMNASLC34A1FDPS | |
| Phosphoric Acid SCHEMBL6869151 | 0.78 | — | — | |
| Phosphoric Acid SCHEMBL27812171 | 0.78 | — | — | |
| Phosphoric Acid SCHEMBL6895934 | 0.78 | — | — | |
| Phosphoric Acid SCHEMBL7601322 | 0.75 | CA2 (0.43) | CA2LMNASLC34A1FDPS | |
| Phosphoric Acid SCHEMBL17555384 | 0.75 | CA2 (0.43) | CA2LMNASLC34A1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108138187-B | Method for increasing replication of circular DNA molecules | 库瑞瓦格房地产有限公司 | 2022-07-19 | — | — | CN | disclosed |
| US-6399335-B1 | MIXING POLYMERASE AND NUCLEOSIDE TRIPHOSPHATE HAVING A GAMMA PHOSPHATE PHOSPHOESTER-LINKED FUNCTIONAL GROUP, INCUBATING SO THAT POLYMERASE CATALYZES CLEAVAGE BETWEEN ALPHA AND BETA PHOSPHATES AND LIBERATES PYROPHOSPHATE WITH FUNCTIONAL GROUP | ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, INC. | 2002-06-04 | — | — | US | disclosed |
| WO-2001048235-A2 | GAMMA-PHOSPHOESTER NUCLEOSIDE TRIPHOSPHATES | ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, INC. (US) | 2001-07-05 | — | — | WO | disclosed |