Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | CDK9 | P50750 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2694375 | 0.79 | EPHX2 (0.57) | EPHX2KDM1AMAPTHTTL3MBTL1 | |
| SCHEMBL3076467 | 0.77 | EPHX2 (0.55) | EPHX2KDM1AMAPTHTTL3MBTL1 | |
| SCHEMBL1689206 | 0.75 | EPHX2 (0.68) | EPHX2KDM1AMAPTHTTL3MBTL1 | |
| SCHEMBL230627 | 0.74 | HDAC4 (0.62) | EPHX2KDM1AMAPTHTTL3MBTL1 | |
| SCHEMBL3342586 | 0.73 | L3MBTL1 (0.80) | EPHX2MAPTHTTL3MBTL1KDM4E | |
| SCHEMBL10494611 | 0.73 | MAPT (0.58) | EPHX2KDM1AMAPTHTTL3MBTL1 | |
| SCHEMBL13655631 | 0.73 | EPHX2 (0.50) | EPHX2KDM1AMAPTHTTL3MBTL1 | |
| SCHEMBL10494610 | 0.73 | MAPT (0.58) | EPHX2KDM1AMAPTHTTL3MBTL1 | |
| SCHEMBL9126255 | 0.72 | L3MBTL1 (0.72) | EPHX2MAPTL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL564081 | 0.72 | KDM1A (0.58) | EPHX2KDM1AMAPTHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1226284-C | N-sulphonyl and N-sulphinyl phenylglycinamide | SYNGENTA PARTICIPATIONS AG (CH) | 2005-11-09 | — | — | CN | disclosed |
| CN-1226284-C | N-sulphonyl and N-sulphinyl phenylglycinamide | SYNGENTA PARTICIPATIONS AG (CH) | 2005-11-09 | — | — | CN | disclosed |
| US-6391918-B1 | FUNGICIDES | SYNGENTA CROP PROTECTION, INC. | 2002-05-21 | — | — | US | disclosed |
| CN-1291973-A | N-sulphonyl and N-sulphinyl phenylglycinamide | NOVARTIS AG (CH) | 2001-04-18 | — | — | CN | disclosed |