Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Catechol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | GMNN | O75496 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.59 |
| ▸ | FYN | P06241 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | CA3 | P07451 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Catechol SCHEMBL2581350 | 0.94 | ALDH1A1 (0.67) | ALDH1A1MAPTHPGDHSD17B10ALOX15 | |
| Catechol SCHEMBL29287077 | 0.86 | ALDH1A1 (0.56) | ALDH1A1MAPTHPGDHSD17B10ALOX15 | |
| Catechol SCHEMBL23241892 | 0.85 | ALDH1A1 (0.62) | ALDH1A1MAPTHPGDHSD17B10ALOX15 | |
| Catechol SCHEMBL11566875 | 0.84 | CA2 (0.71) | ALDH1A1MAPTHPGDHSD17B10ALOX15 | |
| Catechol SCHEMBL7569845 | 0.84 | CA2 (0.71) | ALDH1A1MAPTHPGDHSD17B10ALOX15 | |
| Catechol SCHEMBL27799225 | 0.82 | ALDH1A1 (0.59) | ALDH1A1MAPTHPGDHSD17B10ALOX15 | |
| Catechol SCHEMBL27754508 | 0.82 | ALDH1A1 (0.59) | ALDH1A1MAPTHPGDHSD17B10ALOX15 | |
| Catechol SCHEMBL665292 | 0.81 | ALDH1A1 (0.67) | ALDH1A1MAPTHPGDHSD17B10ALOX15 | |
| Questiomycin B SCHEMBL27305569 | 0.81 | ALOX15 (0.75) | ALDH1A1MAPTHPGDHSD17B10ALOX15 | |
| Catechol SCHEMBL23801229 | 0.81 | ALDH1A1 (0.77) | ALDH1A1MAPTHPGDHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399552-B1 | MIXTURE OF FLUORIDE REDUCING AGENT, ORGANIC ACID AND WATER | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2002-06-04 | — | — | US | disclosed |