Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM3 | Q86V86 | 2/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.41 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.40 |
| ▸ | GABRE | P78334 | 1/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL148467 | 0.89 | TDO2 (0.54) | PIM3PIM1PKN1PKN2BTK | |
| SCHEMBL147833 | 0.77 | PIM3 (0.50) | PIM3PIM1BTKKIF11KDM4E | |
| SCHEMBL148354 | 0.75 | PIM1 (0.45) | PIM3PIM1DYRK1ABTKTDO2 | |
| SCHEMBL148605 | 0.74 | PIM1 (0.44) | PIM3PIM1DYRK1ABTKKDM4E | |
| SCHEMBL28165763 | 0.74 | PIM3 (0.55) | PIM3PIM1GABRPGABRDGABRA1 | |
| SCHEMBL149085 | 0.73 | BCHE (0.46) | PIM3PIM1DYRK1AGABRA1GABRG2 | |
| SCHEMBL8910145 | 0.72 | PIM3 (0.57) | PIM3PIM1DYRK1AGABRPGABRD | |
| Carbamic Acid SCHEMBL3414543 | 0.72 | PKN1 (0.44) | DYRK1APKN1PKN2GABRPGABRD | |
| SCHEMBL28856729 | 0.70 | PIM1 (0.51) | PIM3PIM1KIF11KDM4EALDH1A1 | |
| SCHEMBL28481860 | 0.70 | KIF11 (0.56) | PIM3PIM1GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399631-B1 | 3-AMIDO OR 3-SULFONAMIDO; EATING DISORDERS IN HUMANS, DOGS AND CATS | PFIZER INC. | 2002-06-04 | — | — | US | disclosed |