SCHEMBL7723870

SCHEMBL7723870

Oc1ccccc1-c1ccc(Cl)c(Cl)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 5/20 0.54
ESR2 Q92731 2/20 0.53
ALDH1A1 P00352 2/20 0.52
HSD17B10 Q99714 2/20 0.52
HPGD P15428 1/20 0.52
BCL2L1 Q07817 1/20 0.52
PTGER1 P34995 1/20 0.50
PTGER3 P43115 1/20 0.50
PTGER2 P43116 1/20 0.50
APP P05067 1/20 0.48
RORB Q92753 1/20 0.46
CYP1B1 Q16678 1/20 0.45
QPCT Q16769 1/20 0.45
QPCTL Q9NXS2 1/20 0.45
PTGES2 Q9H7Z7 1/20 0.44
KDR P35968 1/20 0.44
HSD11B1 P28845 1/20 0.44
MEN1 O00255 1/20 0.43
HTT P42858 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7789344 0.88 ESR2 (0.64) ESR2ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL20635185 0.81 AHR (0.47) AHRESR2HSD17B10PTGER1PTGER3
Hydrochloric Acid SCHEMBL30065790 0.81 CYP3A4 (0.59) ESR2ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL3111742 0.80 AHR (0.60) AHRPTGER1PTGER3PTGER2RORB
SCHEMBL29617534 0.80 AHR (0.60) AHRPTGER1PTGER3PTGER2RORB
SCHEMBL3842572 0.78 AHR (0.52) AHRESR2ALDH1A1HSD17B10HPGD
SCHEMBL714236 0.77 ALDH1A1 (0.83) ESR2ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL29443997 0.77 ALDH1A1 (0.83) ESR2ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL8853315 0.76 ALDH1A1 (0.65) ESR2ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL28742545 0.76 APP (0.82) ESR2ALDH1A1HSD17B10HPGDBCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100335559-C High optical contrast resin composition and electronic package utilizing same IBM (US) 2007-09-05 CN disclosed
US-6337375-B1 RESIN WITH COLOR AND FLUORESCING AGENT INTERNATIONAL BUSINESS MACHINES CORPORATION 2002-01-08 US disclosed
EP-1145083-A2 HYBRID SURFACE MODIFICATION PROCESS AND ARTICLE BMC Industries, Inc. (US) 2001-10-17 EP disclosed
US-6190759-B1 ELECTRONIC PACKAGE COMPRISING DIELECTRIC LAYER AND CONDUCTIVE LAYER, SAID DIELECTRIC LAYER INCLUDING REINFORCING MATERIAL, RESIN MATERIAL SELECTED FROM EPOXY, CYANATE AND BISMALEIMIDE RESINS, COLORING AGENT, AND FLUORESCING AGENT INTERNATIONAL BUSINESS MACHINES CORPORATION 2001-02-20 US disclosed
US-6187417-B1 Substrate having high optical contrast and method of making same INTERNATIONAL BUSINESS MACHINES CORPORATION 2001-02-13 US disclosed
WO-2000073856-A2 PATTERN FORMING PROCESS COMPRISING CHEMICAL MACHINING AND ELECTRICAL DISCHARGE MACHINING BMC INDUSTRIES, INC. (US) 2000-12-07 WO disclosed
CN-1226580-A High optical contrast resin composition and electronic package utilizing same IBM (US) 1999-08-25 CN disclosed
EP-0534204-B1 Base developable negative photoresist and use thereof IBM (US) 1997-06-04 EP disclosed
US-5629355-A Polymeric sulfonium salt photoinitiators INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1997-05-13 US disclosed
US-5605781-A Photosensitive composition with cyanate esters and use thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1997-02-25 US disclosed
US-4483961-A Polymeric cyclopentadiene derivatives, method for preparing and use thereof ASHLAND OIL, INC. (US) 1984-11-20 US disclosed
US-4482653-A Cyclopentadiene derivatives, method for preparing, and use thereof ASHLAND OIL, INC. (US) 1984-11-13 US disclosed
US-4464521-A EPOXIDIZED FULVENES AS BINDER FOR AGGREGATE; FOUNDRY BINDERS ASHLAND OIL, INC. (US) 1984-08-07 US disclosed
US-4412088-A CURABLE BINDER COMPOSITIONS ASHLAND OIL, INC. (US) 1983-10-25 US disclosed
US-4410647-A POLYANHYDRIDE, 2-ACETOXYTRIMETHYLENEBIS/ANHYDROTRIMELLITATE/ INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1983-10-18 US disclosed
US-4390675-A EPOXYFULVENE, ACID CATALYST ASHLAND OIL, INC. (US) 1983-06-28 US disclosed
EP-0053280-A1 Sealing composition, method for preparing said composition, integrated circuit module sealed therewith, and process for sealing International Business Machines Corporation (US) 1982-06-09 EP disclosed
EP-0009190-B1 CURABLE COMPOSITION USEFUL FOR SCREEN-PRINTING, A CURED COATING COMPRISING SAID COMPOSITION AND PROCESS FOR SOLDERING PRINTED CIRCUIT BOARDS USING SAID COMPOSITION International Business Machines Corporation (US) 1982-04-28 EP disclosed
US-4292230-A Screen-printing composition and use thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1981-09-29 US disclosed
EP-0009190-A1 Curable composition useful for screen-printing, a cured coating comprising said composition and process for soldering printed circuit boards using said composition International Business Machines Corporation (US) 1980-04-02 EP disclosed