Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 4/20 | 0.64 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.53 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | QPCT | Q16769 | 1/20 | 0.45 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7723870 | 0.88 | AHR (0.54) | ESR2APPALDH1A1HSD17B10HPGD | |
| SCHEMBL18238557 | 0.82 | ESR2 (0.58) | ESR2APPHSD17B1HSD17B2PTGS2 | |
| SCHEMBL19173098 | 0.82 | MCL1 (0.58) | ESR2APPHSD17B1HSD17B2PTGS2 | |
| Hydrochloric Acid SCHEMBL30065790 | 0.81 | CYP3A4 (0.59) | ESR2APPALDH1A1HSD17B10HPGD | |
| SCHEMBL28742545 | 0.80 | APP (0.82) | ESR2APPALDH1A1HSD17B10HPGD | |
| SCHEMBL28202577 | 0.79 | ESR2 (0.77) | ESR2APPHSD17B1HSD17B2ALDH1A1 | |
| SCHEMBL278316 | 0.79 | ESR2 (0.77) | ESR2APPHSD17B1HSD17B2ALDH1A1 | |
| SCHEMBL29911026 | 0.79 | ESR2 (0.77) | ESR2APPHSD17B1HSD17B2ALDH1A1 | |
| SCHEMBL1513545 | 0.78 | ESR2 (1.00) | ESR2HSD17B1HSD17B2ALDH1A1HSD17B10 | |
| SCHEMBL8926730 | 0.78 | ESR2 (0.53) | ESR2APPHSD17B1HSD17B2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020189681-A1 | POLYCARBONATE RESIN COMPOSITION, PRODUCTION METHOD THEREFOR, MASTERBATCH PELLET, AND MOLDED BODY | 宇部マテリアルズ株式会社 | 2020-09-24 | — | — | WO | disclosed |
| EP-0934323-B1 | SOLUBLE MONO-ALKYL STANNOIC ACID CATALYST AND ITS USE IN PREPARING HIGH MOLECULAR WEIGHT POLYESTERS | DU PONT (US) | 2001-12-12 | — | — | EP | disclosed |
| US-5891985-A | Soluble mono-alkyl stannoic acid catalyst and its use in preparing high molecular weight polyesters | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-04-06 | — | — | US | disclosed |
| EP-0564517-A1 | ARYLCYCLOBUTENE TERMINATED CARBONATE POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1993-10-13 | — | — | EP | disclosed |
| WO-1992011309-A1 | ARYLCYCLOBUTENE TERMINATED CARBONATE POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |