Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.51 |
| ▸ | EHMT1 | Q9H9B1 | 4/20 | 0.50 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.50 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.50 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.50 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.50 |
| ▸ | GAPDH | P04406 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | STAT6 | P42226 | 1/20 | 0.50 |
| ▸ | PI4KA | P42356 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7723981 | 0.93 | EHMT1 (0.54) | ADORA3ADORA2AADORA1EHMT1EHMT2 | |
| SCHEMBL7733959 | 0.89 | AHCY (0.53) | ADORA3ADORA2AADORA1EHMT1EHMT2 | |
| SCHEMBL7732659 | 0.84 | AHCY (0.52) | ADORA3ADORA2AADORA1EHMT1EHMT2 | |
| SCHEMBL7733927 | 0.84 | AHCY (0.52) | ADORA3ADORA2AADORA1EHMT1EHMT2 | |
| SCHEMBL5349884 | 0.83 | HSP90B1 (0.57) | ADORA3ADORA2AADORA1EHMT1EHMT2 | |
| SCHEMBL7734141 | 0.81 | ADORA3 (0.49) | ADORA3ADORA2AADORA1ADORA2BPRMT5 | |
| SCHEMBL7735006 | 0.80 | AHCY (0.52) | ADORA3ADORA2AADORA1EHMT1EHMT2 | |
| SCHEMBL5361659 | 0.79 | ADORA3 (0.57) | ADORA3ADORA2AADORA1EHMT1EHMT2 | |
| SCHEMBL5354507 | 0.78 | ADORA3 (0.56) | ADORA3ADORA2AADORA1EHMT1EHMT2 | |
| SCHEMBL7734952 | 0.78 | PRMT5 (0.60) | ADORA3ADORA2AADORA1ADORA2BPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407076-B1 | ANTIISCHEMIC, ANTILIPOLYTIC, ANTICONVULSANT AND HYPOTENSIVE AGENTS; CARDIOVASCULAR AND NERVOUS SYSTEM DISORDERS; ATHEROSCLEROSIS | SMITHKLINE BEECHAM CORPORATION | 2002-06-18 | — | — | US | claimed |