Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.49 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.48 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.48 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.48 |
| ▸ | GAPDH | P04406 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | STAT6 | P42226 | 1/20 | 0.48 |
| ▸ | PI4KA | P42356 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.48 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.48 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7723981 | 0.82 | EHMT1 (0.54) | ADORA3ADORA2AADORA1PRMT5WDR77 | |
| SCHEMBL7723990 | 0.81 | ADORA3 (0.51) | ADORA3ADORA2AADORA1PRMT5WDR77 | |
| SCHEMBL7734952 | 0.77 | PRMT5 (0.60) | ADORA3ADORA2AADORA1PRMT5WDR77 | |
| SCHEMBL800351 | 0.75 | PRMT5 (0.64) | ADORA3ADORA2AADORA1PRMT5WDR77 | |
| SCHEMBL800776 | 0.75 | PRMT5 (0.64) | ADORA3ADORA2AADORA1PRMT5WDR77 | |
| SCHEMBL25390909 | 0.74 | AHCY (0.66) | ADORA3ADORA2AADORA1PRMT5WDR77 | |
| SCHEMBL4650654 | 0.74 | AHCY (0.66) | ADORA3ADORA2AADORA1PRMT5WDR77 | |
| SCHEMBL25390247 | 0.74 | AHCY (0.66) | ADORA3ADORA2AADORA1PRMT5WDR77 | |
| SCHEMBL8990546 | 0.74 | AHCY (0.66) | ADORA3ADORA2AADORA1PRMT5WDR77 | |
| SCHEMBL26239612 | 0.74 | AHCY (0.66) | ADORA3ADORA2AADORA1PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407076-B1 | ANTIISCHEMIC, ANTILIPOLYTIC, ANTICONVULSANT AND HYPOTENSIVE AGENTS; CARDIOVASCULAR AND NERVOUS SYSTEM DISORDERS; ATHEROSCLEROSIS | SMITHKLINE BEECHAM CORPORATION | 2002-06-18 | — | — | US | claimed |