Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9921278 | 0.84 | KDM4E (0.60) | ALDH1A1MAPTKDM4EKMT2ACA1 | |
| SCHEMBL7729391 | 0.82 | CA1 (0.68) | ALDH1A1MAPTKDM4EKMT2ACA1 | |
| SCHEMBL9254644 | 0.80 | ALDH1A1 (0.55) | ALDH1A1MAPTKDM4EKMT2ARAB9A | |
| SCHEMBL8763632 | 0.80 | ALDH1A1 (1.00) | ALDH1A1MAPTKDM4EKMT2ARAB9A | |
| SCHEMBL24820550 | 0.80 | ALDH1A1 (1.00) | ALDH1A1MAPTKMT2ARAB9AGAA | |
| SCHEMBL375579 | 0.80 | ALDH1A1 (0.59) | ALDH1A1MAPTKDM4ERAB9ACFTR | |
| SCHEMBL6366964 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4EKMT2ARAB9A | |
| SCHEMBL30385607 | 0.78 | KDM4E (0.55) | ALDH1A1MAPTKDM4EKMT2ACA1 | |
| Hydrochloric Acid SCHEMBL27744263 | 0.78 | ALDH1A1 (0.57) | ALDH1A1MAPTKDM4ERAB9ACFTR | |
| Acetic Acid SCHEMBL28650473 | 0.75 | KDM4E (0.56) | ALDH1A1MAPTKDM4EKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420367-B1 | RAS GENE | SHIONOGO & CO., LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-1097933-A1 | PYRIMIDINE DERIVATIVES EXHIBITING ANTITUMOR ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2001-05-09 | — | — | EP | disclosed |