Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14628078 | 0.87 | DPP4 (0.47) | KMT2AMEN1CYP3A4HPGDMAPT | |
| SCHEMBL18562109 | 0.83 | TSHR (0.47) | KMT2AMEN1CYP3A4HPGDMAPT | |
| SCHEMBL13750377 | 0.83 | MMP2 (0.51) | KMT2AMEN1CYP3A4HPGDMAPT | |
| SCHEMBL6359191 | 0.83 | KMT2A (0.48) | KMT2AMEN1CYP3A4HPGDMAPT | |
| SCHEMBL2323847 | 0.83 | MEN1 (0.48) | KMT2AMEN1CYP3A4HPGDMAPT | |
| SCHEMBL6359192 | 0.83 | KMT2A (0.48) | KMT2AMEN1CYP3A4HPGDMAPT | |
| SCHEMBL7468481 | 0.81 | SIGMAR1 (0.51) | KMT2AMEN1CYP3A4HPGDMAPT | |
| SCHEMBL17944509 | 0.81 | SIGMAR1 (0.51) | KMT2AMEN1CYP3A4HPGDMAPT | |
| SCHEMBL10192651 | 0.81 | KMT2A (0.51) | KMT2AMEN1CYP3A4HPGDMAPT | |
| SCHEMBL10192637 | 0.81 | KMT2A (0.51) | KMT2AMEN1CYP3A4HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6770640-B1 | EMPHYSEMA | AVENTIS PHARMACEUTICALS INC. | 2004-08-03 | — | — | US | disclosed |