Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 2/20 | 0.50 |
| ▸ | ACE | P12821 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17944509 | 1.00 | SIGMAR1 (0.51) | SIGMAR1MMEACENPSR1PTPN1 | |
| SCHEMBL17943865 | 0.87 | SIGMAR1 (0.49) | SIGMAR1MMEACEMDM2CYP1A2 | |
| SCHEMBL11764962 | 0.86 | PLOD2 (0.56) | MEN1CYP3A4KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL7473135 | 0.86 | FPR2 (0.58) | MAPTALOX15KMT2AMMP2MMP9 | |
| SCHEMBL11764959 | 0.86 | PLOD2 (0.56) | MEN1CYP3A4KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL547297 | 0.84 | NAALAD2 (0.55) | MMENPSR1NAALAD2CYP1A2MMP2 | |
| SCHEMBL1272029 | 0.84 | NAALAD2 (0.55) | MMENPSR1NAALAD2CYP1A2MMP2 | |
| SCHEMBL547710 | 0.84 | NAALAD2 (0.55) | MMENPSR1NAALAD2CYP1A2MMP2 | |
| SCHEMBL17693619 | 0.84 | CA1 (0.50) | MMEACEKDM4EMEN1ALOX15 | |
| SCHEMBL9340320 | 0.83 | NAALAD2 (0.54) | MMENPSR1NAALAD2CYP1A2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1153050-A4 | AMINO-KETONE SOLID SUPPORT TEMPLATES | ADVANCED SYNTECH LLC (US) | 2002-11-27 | — | — | EP | disclosed |
| EP-1153050-A1 | AMINO-KETONE SOLID SUPPORT TEMPLATES | Advanced syntech, LLC (US) | 2001-11-14 | — | — | EP | disclosed |
| US-6117940-A | SOLID PHASE SYNTHESIS OF COMPOUNDS SUCH AS THE IMIDAZOLES, BENZODIAZEPINES, PYRAZINES, AND STEROID MIMICS. | ADVANCED SYNTECH, LLC, A KENTUCKY LIMITED LIABILITY CORPORATION | 2000-09-12 | — | — | US | disclosed |
| WO-2000023487-A1 | AMINO-KETONE SOLID SUPPORT TEMPLATES | ADVANCED SYNTECH, LLC (US) | 2000-04-27 | — | — | WO | disclosed |