Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CCR3 | P51677 | 5/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | DRD5 | P21918 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7724365 | 1.00 | KMT2A (0.48) | KMT2ARAB9ACCR3FKBP1AEPHX1 | |
| SCHEMBL7724337 | 0.95 | KMT2A (0.51) | KMT2ARAB9ACCR3EPHX1HTR2A | |
| SCHEMBL7719734 | 0.95 | KMT2A (0.51) | KMT2ARAB9ACCR3EPHX1HTR2A | |
| SCHEMBL7719729 | 0.95 | KMT2A (0.51) | KMT2ARAB9ACCR3EPHX1HTR2A | |
| Hydrochloric Acid SCHEMBL7719913 | 0.93 | KMT2A (0.49) | KMT2ARAB9ACCR3EPHX1HTR2A | |
| Hydrochloric Acid SCHEMBL7719915 | 0.93 | KMT2A (0.49) | KMT2ARAB9ACCR3EPHX1HTR2A | |
| SCHEMBL7729613 | 0.90 | HSD11B1 (0.53) | KMT2ARAB9AEPHX1DRD4KDM1A | |
| SCHEMBL7729620 | 0.90 | HSD11B1 (0.53) | KMT2ARAB9AEPHX1DRD4KDM1A | |
| SCHEMBL7724063 | 0.89 | DRD2 (0.50) | KMT2ARAB9AFKBP1AEPHX1DRD2 | |
| SCHEMBL7724059 | 0.89 | DRD2 (0.50) | KMT2ARAB9AFKBP1AEPHX1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6468998-B1 | ANTAGONIZE SEROTONIN 2 RECEPTORS, SUPPRESS PLATELET AGGREGATION, IMPROVE PERIPHERAL CIRCULATION AND PROMOTE LACHRYMATION | MITSUBISHI PHARMA CORPORATION (JP) | 2002-10-22 | — | — | US | claimed |
| EP-1125922-A1 | PYRROLIDINE COMPOUNDS AND MEDICINAL UTILIZATION THEREOF | Welfide Corporation (JP) | 2001-08-22 | — | — | EP | claimed |
| US-6468998-B1 | ANTAGONIZE SEROTONIN 2 RECEPTORS, SUPPRESS PLATELET AGGREGATION, IMPROVE PERIPHERAL CIRCULATION AND PROMOTE LACHRYMATION | MITSUBISHI PHARMA CORPORATION (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-1125922-A1 | PYRROLIDINE COMPOUNDS AND MEDICINAL UTILIZATION THEREOF | Welfide Corporation (JP) | 2001-08-22 | — | — | EP | disclosed |