Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL165385 | 0.89 | POLB (0.69) | POLBMAPTPKMLMNAALDH1A1 | |
| SCHEMBL2652681 | 0.84 | POLB (0.62) | POLBMAPTPKMLMNAALDH1A1 | |
| SCHEMBL9343618 | 0.82 | PKM (1.00) | POLBMAPTPKMLMNAALDH1A1 | |
| SCHEMBL14024262 | 0.82 | MAPT (0.77) | POLBMAPTPKMLMNAALDH1A1 | |
| SCHEMBL9422194 | 0.81 | POLB (0.59) | POLBMAPTPKMLMNAALDH1A1 | |
| SCHEMBL7717466 | 0.81 | POLB (0.50) | POLBMAPTPKMLMNAALDH1A1 | |
| SCHEMBL1930857 | 0.80 | MAPT (0.74) | POLBMAPTPKMLMNAALDH1A1 | |
| SCHEMBL3161812 | 0.80 | MAPT (0.74) | POLBMAPTPKMLMNAALDH1A1 | |
| SCHEMBL3536505 | 0.78 | POLB (0.71) | POLBMAPTPKMLMNAALDH1A1 | |
| SCHEMBL65266 | 0.78 | MAPT (0.71) | POLBMAPTPKMLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395446-B1 | CONTAINING SULFONYLDIAZOMETHANE COMPOUND AS ACID GENERATOR | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |