Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8054990 | 0.83 | POLB (0.52) | POLBPKMMMP2ALDH1A1SMN1; SMN2 | |
| SCHEMBL7724548 | 0.81 | POLB (0.69) | POLBMAPTPKMPTGS2ALDH1A1 | |
| SCHEMBL7692517 | 0.81 | MMP2 (0.52) | POLBMMP2ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL29904520 | 0.75 | POLB (0.47) | POLBMAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL165385 | 0.74 | POLB (0.69) | POLBMAPTPKMPTGS2ALDH1A1 | |
| SCHEMBL3841202 | 0.73 | MAPT (0.62) | POLBMAPTPKMPTGS2ESR1 | |
| SCHEMBL7721708 | 0.73 | MAPT (0.47) | POLBMAPTPKMPTGS2ESR1 | |
| SCHEMBL2652681 | 0.70 | POLB (0.62) | POLBMAPTPKMPTGS2ALDH1A1 | |
| SCHEMBL7722429 | 0.69 | POLB (0.46) | POLBMAPTPKMPTGS2ESR1 | |
| SCHEMBL9343618 | 0.69 | PKM (1.00) | POLBMAPTPKMPTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395446-B1 | CONTAINING SULFONYLDIAZOMETHANE COMPOUND AS ACID GENERATOR | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |