Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BCL9 | O00512 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7722372 | 0.91 | KMT2A (0.49) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL7721784 | 0.88 | KMT2A (0.41) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL7717473 | 0.87 | KMT2A (0.43) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL7724562 | 0.86 | KMT2A (0.51) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL7724577 | 0.86 | ELANE (0.51) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL7721780 | 0.86 | MAPT (0.50) | KMT2ASMN1; SMN2ELANEMAPTLMNA | |
| SCHEMBL7721776 | 0.85 | KMT2A (0.43) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL7721700 | 0.82 | ELANE (0.42) | SMN1; SMN2ELANEMAPTPOLBPKM | |
| SCHEMBL7695981 | 0.82 | MMP2 (0.39) | SMN1; SMN2ELANERAB9AALDH1A1GAA | |
| SCHEMBL7720645 | 0.81 | KMT2A (0.41) | KMT2ASMN1; SMN2ESR1HIF1ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395446-B1 | CONTAINING SULFONYLDIAZOMETHANE COMPOUND AS ACID GENERATOR | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |