Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7724562 | 0.89 | KMT2A (0.51) | KMT2AACHELMNAESR1HIF1A | |
| SCHEMBL7721788 | 0.88 | MAPT (0.44) | KMT2AACHELMNASMN1; SMN2RAPGEF3 | |
| SCHEMBL7722372 | 0.87 | KMT2A (0.49) | KMT2AACHELMNAESR1HIF1A | |
| SCHEMBL7721774 | 0.85 | ELANE (0.38) | KMT2ALMNASMN1; SMN2RAPGEF3ELANE | |
| SCHEMBL7696174 | 0.85 | LMNA (0.40) | KMT2ALMNARAPGEF4RAPGEF3MEP1B | |
| SCHEMBL7693707 | 0.82 | LMNA (0.42) | KMT2ALMNARAPGEF4RAPGEF3MAPT | |
| SCHEMBL7724577 | 0.82 | ELANE (0.51) | KMT2AACHELMNAESR1HIF1A | |
| SCHEMBL6737115 | 0.81 | PDIA6 (0.41) | NPC1 | |
| SCHEMBL6741894 | 0.81 | PDIA6 (0.41) | NPC1 | |
| SCHEMBL7721784 | 0.81 | KMT2A (0.41) | KMT2ALMNAESR1HIF1ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395446-B1 | CONTAINING SULFONYLDIAZOMETHANE COMPOUND AS ACID GENERATOR | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |