Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.47 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.47 |
| ▸ | METAP2 | P50579 | 10/20 | 0.40 |
| ▸ | METAP1 | P53582 | 5/20 | 0.39 |
| ▸ | LAP3 | P28838 | 2/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | RRM1 | P23921 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14974409 | 0.98 | ANPEP (0.46) | ANPEPDNPEPMETAP2METAP1LAP3 | |
| SCHEMBL12442850 | 0.83 | ALDH1A1 (0.44) | ANPEPDNPEPMETAP2METAP1LAP3 | |
| Hydrochloric Acid SCHEMBL14974306 | 0.82 | DPP7 (0.53) | ANPEPDNPEPMETAP2LAP3RNPEP | |
| Hydrochloric Acid SCHEMBL14974473 | 0.82 | ANPEP (0.44) | ANPEPDNPEPMETAP2METAP1LAP3 | |
| SCHEMBL8138370 | 0.82 | METAP2 (0.42) | ANPEPDNPEPMETAP2METAP1DPP7 | |
| SCHEMBL12413226 | 0.82 | METAP2 (0.42) | ANPEPDNPEPMETAP2METAP1DPP7 | |
| SCHEMBL13934155 | 0.80 | ANPEP (0.41) | ANPEPDNPEPMETAP2METAP1LAP3 | |
| SCHEMBL14974373 | 0.80 | ANPEP (0.41) | ANPEPDNPEPMETAP2METAP1LAP3 | |
| SCHEMBL8280558 | 0.80 | ANPEP (0.41) | ANPEPDNPEPMETAP2METAP1LAP3 | |
| SCHEMBL7734253 | 0.80 | BIRC2 (0.44) | ANPEPDNPEPMETAP2METAP1LAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800434-B2 | Peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION | 2004-10-05 | — | — | US | disclosed |