Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 1/20 | 0.44 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 2/20 | 0.41 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 12/20 | 0.38 |
| ▸ | METAP1 | P53582 | 7/20 | 0.38 |
| ▸ | LAP3 | P28838 | 2/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL418584 | 0.86 | CTSK (0.42) | BIRC2ANPEPDNPEPMETAP2METAP1 | |
| SCHEMBL12442850 | 0.83 | ALDH1A1 (0.44) | ANPEPDNPEPMETAP2METAP1LAP3 | |
| SCHEMBL13707800 | 0.81 | TSHR (0.40) | BIRC2ANPEPDNPEPMETAP2METAP1 | |
| SCHEMBL7724648 | 0.80 | ANPEP (0.47) | ANPEPDNPEPMETAP2METAP1LAP3 | |
| Hydrochloric Acid SCHEMBL14974409 | 0.79 | ANPEP (0.46) | ANPEPDNPEPMETAP2METAP1LAP3 | |
| SCHEMBL13707811 | 0.77 | CYP1A2 (0.51) | ANPEPDNPEPMETAP2METAP1LAP3 | |
| SCHEMBL8373232 | 0.77 | BIRC2 (0.58) | BIRC2TET2RECQL | |
| SCHEMBL14974373 | 0.77 | ANPEP (0.41) | ANPEPDNPEPMETAP2METAP1LAP3 | |
| SCHEMBL6389105 | 0.76 | TET2 (0.48) | BIRC2TET2RECQLMETAP1 | |
| SCHEMBL13305813 | 0.75 | BIRC2 (0.50) | BIRC2TET2RECQLDPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800434-B2 | Peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION | 2004-10-05 | — | — | US | disclosed |