Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7720019 | 0.86 | RAB9A (0.42) | KCNN4HDAC1HDAC6MAPTALDH1A1 | |
| SCHEMBL7730017 | 0.80 | ALDH1A1 (0.53) | KMT2AMEN1CYP2C19MAPTALDH1A1 | |
| SCHEMBL10837067 | 0.79 | KCNN4 (0.62) | KCNN4SRCKMT2AMEN1OPRM1 | |
| SCHEMBL9119027 | 0.76 | CYP2C9 (0.46) | KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL4811115 | 0.75 | KCNN4 (0.56) | KCNN4SRCKMT2AMEN1OPRM1 | |
| SCHEMBL10841865 | 0.72 | KCNN4 (0.53) | KCNN4SRCKMT2AMEN1OPRM1 | |
| SCHEMBL16732028 | 0.71 | KCNN4 (0.67) | KCNN4SRCKMT2AMEN1OPRM1 | |
| SCHEMBL22160044 | 0.71 | MAPK1 (0.43) | KCNN4KMT2ACYP2C19HIF1AHDAC3 | |
| SCHEMBL4022191 | 0.71 | KCNN4 (0.67) | KCNN4SRCKMT2ACYP2C19HIF1A | |
| SCHEMBL728471 | 0.71 | KCNN4 (0.67) | KCNN4SRCKMT2AMEN1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403818-B1 | ONE POT PROCESS STARTING FROM CARBONYL COMPOUND, ALCOHOL, THIOL OR AMINE, AND PROTECTED HYDROXYDICYANO COMPOUND | EISAI CO., LTD. (JP) | 2002-06-11 | — | — | US | disclosed |