Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | SGK1 | O00141 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL731847 | 0.79 | KIF11 (0.40) | PPARAPTPN5KIF11 | |
| SCHEMBL7725823 | 0.76 | KCNN4 (0.51) | MAPTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL5041181 | 0.74 | CYP2C9 (0.49) | CYP2C9PPARGPPARAPTGS2MAPT | |
| SCHEMBL5041186 | 0.74 | CYP2C9 (0.49) | CYP2C9PPARGPPARAPTGS2MAPT | |
| SCHEMBL11599887 | 0.72 | PPARA (0.68) | CYP2C9PPARGPPARAPTGS2MAPT | |
| SCHEMBL31038336 | 0.71 | PPARG (0.39) | PPARGPPARAMAPTKMT2A | |
| SCHEMBL3087883 | 0.70 | CYP2C9 (0.61) | CYP2C9PTGS2MAPTSMN1; SMN2PTPN5 | |
| SCHEMBL1679690 | 0.70 | CYP2C9 (0.61) | CYP2C9PTGS2MAPTSMN1; SMN2PTPN5 | |
| SCHEMBL3060223 | 0.69 | MAPT (0.52) | CYP2C9MAPTSMN1; SMN2PTPN5NPC1 | |
| SCHEMBL7720019 | 0.69 | RAB9A (0.42) | MAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995023139-A1 | OPTICALLY PURE 4-ARYL-2-HYDROXYTETRONIC ACIDS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1995-08-31 | — | — | WO | disclosed |
| US-5399721-A | Anticoagulant; prepared from aldehyde | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1995-03-21 | — | — | US | disclosed |