Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7726088 | 1.00 | PLA2G2A (0.52) | PLA2G2ARAB9AGABRG2GABRB3GABRA3 | |
| SCHEMBL7723443 | 0.92 | MAPT (0.45) | PLA2G2ARAB9ARXFP1KDM4ECYP1A2 | |
| SCHEMBL7723444 | 0.92 | MAPT (0.45) | PLA2G2ARAB9ARXFP1KDM4ECYP1A2 | |
| SCHEMBL7723464 | 0.92 | PLA2G2A (0.46) | PLA2G2ARAB9ARXFP1KDM4ELMNA | |
| SCHEMBL7723465 | 0.92 | PLA2G2A (0.46) | PLA2G2ARAB9ARXFP1KDM4ELMNA | |
| SCHEMBL7724798 | 0.84 | LMNA (0.42) | PLA2G2ARAB9AKDM4ELMNA | |
| SCHEMBL7724793 | 0.84 | LMNA (0.42) | PLA2G2ARAB9AKDM4ELMNA | |
| SCHEMBL7726369 | 0.80 | PLA2G2A (0.48) | PLA2G2ARAB9ARXFP1KDM4ECYP2D6 | |
| SCHEMBL7726371 | 0.80 | PLA2G2A (0.48) | PLA2G2ARAB9ARXFP1KDM4ECYP2D6 | |
| SCHEMBL7720344 | 0.77 | PLA2G2A (0.51) | PLA2G2ARAB9AGABRG2GABRB3GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403586-B1 | Pyridazine derivatives and drugs containing the same as the active ingredient | KOWA CO., LTD. (JP) | 2002-06-11 | — | — | US | disclosed |
| EP-1061077-A1 | NOVEL PYRIDAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | Kowa Co., Ltd. (JP) | 2000-12-20 | — | — | EP | disclosed |