Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.42 |
| ▸ | ANPEP | P15144 | 3/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7726102 | 1.00 | MMP2 (0.42) | MMP2ANPEPNR1H2NR1H3CA12 | |
| SCHEMBL7731145 | 0.84 | ALDH1A1 (0.43) | MMP2ANPEPMEN1KMT2AALDH1A1 | |
| SCHEMBL7731141 | 0.84 | ALDH1A1 (0.43) | MMP2ANPEPMEN1KMT2AALDH1A1 | |
| SCHEMBL7722294 | 0.81 | ANPEP (0.52) | MMP2ANPEPALDH1A1 | |
| SCHEMBL7722292 | 0.81 | ANPEP (0.52) | MMP2ANPEPALDH1A1 | |
| SCHEMBL7805563 | 0.81 | MMP2 (0.48) | MMP2ANPEPNR1H2NR1H3PTPN1 | |
| SCHEMBL489252 | 0.81 | MMP2 (0.48) | MMP2ANPEPNR1H2NR1H3PTPN1 | |
| SCHEMBL1154972 | 0.81 | MMP2 (0.48) | MMP2ANPEPNR1H2NR1H3PTPN1 | |
| SCHEMBL5058842 | 0.81 | MMP2 (0.48) | MMP2ANPEPNR1H2NR1H3PTPN1 | |
| SCHEMBL5691732 | 0.81 | MMP2 (0.48) | MMP2ANPEPNR1H2NR1H3PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399629-B1 | PYRROLIDINES AND PIPERIDINES FOR TREATING MICROBIAL INFECTIONS BY REDUCING EXPORT OF COADMINISTERED ANTIMICROBIAL AGENT OR COMPOUND SYNTHESIZED BY MICROBES FOR THEIR GROWTH; REDUCING IN VIVO AVAILABILITY | MICROCIDE PHARMACEUTICALS, INC. | 2002-06-04 | — | — | US | disclosed |
| WO-2000001714-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-01-13 | — | — | WO | disclosed |