Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8520467 | 0.88 | KDM4E (0.59) | KDM4EMEN1KMT2AL3MBTL1MAPT | |
| Benzophenone SCHEMBL7590791 | 0.82 | ALDH1A1 (0.69) | ALDH1A1RAB9AHPGDKDM4ELMNA | |
| SCHEMBL11784730 | 0.77 | ALDH1A1 (0.62) | ALDH1A1RAB9AHPGDKDM4ELMNA | |
| SCHEMBL4413289 | 0.76 | KDM4E (0.60) | ALDH1A1RAB9AHPGDKDM4ELMNA | |
| SCHEMBL7735715 | 0.75 | ALDH1A1 (0.67) | ALDH1A1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL39036 | 0.74 | TGM2 (0.72) | ALDH1A1RAB9AHPGDLMNAMEN1 | |
| SCHEMBL11789125 | 0.74 | ALDH1A1 (0.70) | ALDH1A1RAB9AHPGDLMNAMEN1 | |
| SCHEMBL13652520 | 0.74 | ALDH1A1 (1.00) | ALDH1A1RAB9AHPGDKDM4ELMNA | |
| SCHEMBL12263890 | 0.74 | ALDH1A1 (0.70) | ALDH1A1RAB9AHPGDLMNAMEN1 | |
| SCHEMBL10813985 | 0.74 | ALDH1A1 (0.70) | ALDH1A1RAB9AHPGDKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410792-B1 | OBESITY DISEASES | BAYER CORPORATION | 2002-06-25 | — | — | US | disclosed |
| US-6048900-A | FOR TREATING EATING DISORDERS, INSULIN RESISTANT DIABETES, HYPERTENSION, HYPERLIPEMIA | BAYER CORPORATION (US) | 2000-04-11 | — | — | US | disclosed |