Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 2/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7726470 | 0.83 | MAPK1 (0.61) | CYP1A2RECQLPOLBNPC1RAB9A | |
| SCHEMBL12302912 | 0.81 | MTNR1A (0.73) | POLBNPC1RAB9AMTNR1AMTNR1B | |
| SCHEMBL4720318 | 0.80 | MTNR1A (0.82) | POLBNPC1RAB9AMTNR1AMTNR1B | |
| SCHEMBL6070016 | 0.80 | CYP1A2 (0.63) | CYP1A2RECQLALDH1A1KMT2AMAPT | |
| SCHEMBL7722861 | 0.80 | CYP1A2 (0.63) | CYP1A2RECQLPOLBNPC1RAB9A | |
| SCHEMBL25938747 | 0.80 | MTNR1A (0.71) | POLBNPC1RAB9AMTNR1AMTNR1B | |
| SCHEMBL30605277 | 0.80 | MTNR1A (0.71) | POLBNPC1RAB9AMTNR1AMTNR1B | |
| SCHEMBL10742560 | 0.78 | CYP1A2 (0.68) | CYP1A2RECQLPOLBRAB9AALDH1A1 | |
| SCHEMBL22302859 | 0.78 | ALDH1A1 (0.52) | POLBNPC1RAB9AMTNR1AMTNR1B | |
| SCHEMBL31300404 | 0.77 | POLB (0.55) | POLBNPC1RAB9AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6391887-B1 | ANTIINFLAMMATORY AGENTS; AUTOIMMUNE DISEASE; CARDIOVASCULAR DISORDERS | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-05-21 | — | — | US | disclosed |