Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20239041 | 0.88 | DHFR (0.55) | DHFRL3MBTL1MAPK1MGLLALDH1A1 | |
| SCHEMBL14718117 | 0.87 | DHFR (0.52) | DHFRL3MBTL1MAPK1MGLL | |
| SCHEMBL8532957 | 0.84 | DHFR (0.46) | DHFRL3MBTL1MAPK1MGLLALDH1A1 | |
| SCHEMBL471847 | 0.83 | DHFR (0.51) | DHFRL3MBTL1MAPK1MGLLALDH1A1 | |
| SCHEMBL29059950 | 0.82 | DHFR (0.40) | DHFRL3MBTL1MAPK1MGLLALDH1A1 | |
| SCHEMBL2779445 | 0.82 | DHFR (0.48) | DHFRL3MBTL1MAPK1MGLLALDH1A1 | |
| SCHEMBL1644094 | 0.82 | DHFR (0.50) | DHFRL3MBTL1MAPK1MGLL | |
| SCHEMBL233960 | 0.82 | ALDH1A1 (0.42) | MAPK1ALDH1A1CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL21801767 | 0.80 | DHFR (0.59) | DHFRL3MBTL1MAPK1MGLLALDH1A1 | |
| SCHEMBL29374975 | 0.80 | DHFR (0.59) | DHFRL3MBTL1MAPK1MGLLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403757-B1 | MODIFIED POLYAMIDE RESIN OBTAINED FROM REACTION OF ACID ANHYDRIDE COMPOUND WITH EPOXY-TERMINATED POLYAMIDE | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISAH (JP) | 2002-06-11 | — | — | US | disclosed |