SCHEMBL233960

SCHEMBL233960

COC(=O)c1cccc(CC2CO2)c1C(=O)OC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.42
LMNA P02545 2/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
KDM4E B2RXH2 4/20 0.39
HSD17B10 Q99714 2/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 2/20 0.39
SIRT1 Q96EB6 1/20 0.39
CFTR P13569 1/20 0.38
ALOX5 P09917 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
MAPK8 P45983 1/20 0.38
MAPK9 P45984 1/20 0.38
MAPK10 P53779 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11422508 0.82 KDM4E (0.45) ALDH1A1LMNAKDM4EHSD17B10HPGD
SCHEMBL7727735 0.82 DHFR (0.49) ALDH1A1TSHRSMN1; SMN2MAPK1CYP3A4
SCHEMBL1177373 0.82 ALDH1A1 (0.36) ALDH1A1LMNACA12CA1CA2
SCHEMBL3667908 0.78 CA1 (0.52) ALDH1A1LMNACA12CA1CA2
SCHEMBL5772033 0.78 CA1 (0.52) ALDH1A1LMNACA12CA1CA2
SCHEMBL8478378 0.77 ALDH1A1 (0.50) ALDH1A1LMNACA12CA1CA2
SCHEMBL8478375 0.77 ALDH1A1 (0.50) ALDH1A1LMNACA12CA1CA2
SCHEMBL3896645 0.76 FOLH1 (0.41) ALDH1A1KDM4EHSD17B10HPGDTSHR
SCHEMBL1424324 0.75 ALDH1A1 (0.53) ALDH1A1LMNACA12CA1CA2
SCHEMBL1962306 0.75 ALDH1A1 (0.49) ALDH1A1LMNACA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5990204-A HIGH HARDNESS; DIELECTRICS; SHEETING PROPERTIES; CORROSION RESISTANCE FOR METALS; GASKETS; SEALS; HARD BUTYL RUBBER ROLL; PACKING USED AT THE JOINT OF METAL PIPE; O-RING; PACKING FOR BATTERY; SEALS FOR ELECTROLYTIC CONDENSER ONIZAWA MASAO (JP) 1999-11-23 US claimed
EP-0353734-A2 Thermosetting composition NIPPON PAINT CO., LTD. (JP) 1990-02-07 EP claimed
US-12617753-B2 Urea derivatives and their use as curatives and curative accelerators for resin systems HEXCEL COMPOSITES LIMITED (GB) 2026-05-05 US disclosed
EP-4680659-A1 USE OF HYDROXY SUBSTITUTED URONES AS CURE ACCELERATORS Hexcel Composites Limited (GB) 2026-01-21 EP disclosed
EP-3959217-B1 IMPROVEMENTS IN OR RELATING TO CURATIVES HEXCEL COMPOSITES LTD (GB) 2025-10-15 EP disclosed
EP-4524197-A1 POLYALKYLENE TEREPHTHALATE RESIN COMPOSITION AND RESIN MOLDED ARTICLE Polyplastics Co., Ltd. (JP) 2025-03-19 EP disclosed
US-20240383845-A1 NAPHTHALENEDITHIOL AND DERIVATIVE THEREOF, AND PRODUCTION PROCESS AND USE FOR THE SAME SUGAI CHEMICAL INDUSTRY CO., LTD. (JP) 2024-11-21 US disclosed
WO-2024194067-A1 USE OF HYDROXY SUBSTITUTED URONES AS CURE ACCELERATORS HEXCEL COMPOSITES LIMITED (GB) 2024-09-26 WO disclosed
US-20240262790-A1 UREA DERIVATIVES AND THEIR USE AS CURATIVES AND CURATIVE ACCELERATORS FOR RESIN SYSTEMS HEXCEL COMPOSITES LIMITED (GB) 2024-08-08 US disclosed
CN-116234846-B Resin composition and molded article 株式会社可乐丽 2024-07-02 CN disclosed
EP-4378928-A1 NAPHTHALENE DITHIOL AND DERIVATIVE THEREOF, AND PRODUCTION METHODS AND USES FOR SAME SUGAI CHEMICAL INDUSTRY CO., LTD. (JP) 2024-06-05 EP disclosed
US-5990204-A HIGH HARDNESS; DIELECTRICS; SHEETING PROPERTIES; CORROSION RESISTANCE FOR METALS; GASKETS; SEALS; HARD BUTYL RUBBER ROLL; PACKING USED AT THE JOINT OF METAL PIPE; O-RING; PACKING FOR BATTERY; SEALS FOR ELECTROLYTIC CONDENSER ONIZAWA MASAO (JP) 1999-11-23 US disclosed
US-5789354-A MODIFIED SILICONE OIL, CURING AGENT AND AN OIL OR GREASE NTN CORPORATION (JP) 1998-08-04 US disclosed
US-5762423-A Bearing device, solid resin lubricating composition and porous oil-impregnated bearing NTN CORPORATION (JP) 1998-06-09 US disclosed
US-5705602-A Process for the production of star-like or comb-like branched aliphatic polyamino compound and curable resin composition TOYO INK MANUFACTURING CO., LTD. (JP) 1998-01-06 US disclosed
EP-0735076-A1 Process for the production of star-like or comb-like branched aliphatic polyamino compound and curable resin composition TOYO INK MANUFACTURING CO., LTD. (JP) 1996-10-02 EP disclosed
EP-0353734-A2 Thermosetting composition NIPPON PAINT CO., LTD. (JP) 1990-02-07 EP disclosed
US-4189548-A NOVEL COPOLYMER PRODUCED BY CATIONIC POLYMERIZATION OF A PETROLEUM DISTILLATE, A DICYCLOPENTADIENE OR A VINYL AROMATIC HYDROCARBON WITH A HIGH BOILING, OXIDATION BY-PRODUCT MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1980-02-19 US disclosed
US-4179550-A CATIONICALLY POLYMERIZING PETROLEUM FRACTIONS, ADDING PHENOLIC OR NAPHTHOLIC RESIDUES MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1979-12-18 US disclosed
US-4179417-A CARBOXYL OR HYDROXY POLYMER DAINIPPON INK & CHEMICALS INC. (JP) 1979-12-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12617753-B2 Urea derivatives and their use as curatives and curative accelerators for resin systems UTS2R, UPP1, XDH ALDH1A1 2551/4885LMNA 280/4885CA12 4507/4885
US-20240383845-A1 NAPHTHALENEDITHIOL AND DERIVATIVE THEREOF, AND PRODUCTION PROCESS AND USE FOR THE SAME HSD11B1, DHCR7, CYP17A1 ALDH1A1 297/4885LMNA 2311/4885CA12 2146/4885
US-20240262790-A1 UREA DERIVATIVES AND THEIR USE AS CURATIVES AND CURATIVE ACCELERATORS FOR RESIN SYSTEMS UMPS, UTS2R, UNG ALDH1A1 1390/4885LMNA 788/4885CA12 4248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.