Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8135118 | 0.80 | P2RX7 (0.31) | P2RX7 | |
| SCHEMBL31741236 | 0.75 | — | — | |
| SCHEMBL8135439 | 0.71 | NPFFR1 (0.33) | P2RX7 | |
| SCHEMBL8150964 | 0.71 | NPFFR1 (0.33) | P2RX7 | |
| SCHEMBL3187773 | 0.70 | HDAC6 (0.36) | — | |
| SCHEMBL7023795 | 0.66 | CA14 (0.39) | — | |
| SCHEMBL1949583 | 0.65 | CA12 (0.34) | — | |
| SCHEMBL1689401 | 0.65 | HDAC6 (0.37) | — | |
| SCHEMBL19608874 | 0.65 | FPR3 (0.32) | — | |
| SCHEMBL11031055 | 0.65 | SCN4A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399629-B1 | PYRROLIDINES AND PIPERIDINES FOR TREATING MICROBIAL INFECTIONS BY REDUCING EXPORT OF COADMINISTERED ANTIMICROBIAL AGENT OR COMPOUND SYNTHESIZED BY MICROBES FOR THEIR GROWTH; REDUCING IN VIVO AVAILABILITY | MICROCIDE PHARMACEUTICALS, INC. | 2002-06-04 | — | — | US | disclosed |