Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.33 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8135439 | 1.00 | NPFFR1 (0.33) | NPFFR1NPFFR2MEN1ALDH1A1TSHR | |
| SCHEMBL8135118 | 0.87 | P2RX7 (0.31) | MEN1KMT2AP2RX7 | |
| SCHEMBL7728931 | 0.77 | HCRTR2 (0.34) | MEN1ALDH1A1TSHRKMT2AEPHX1 | |
| SCHEMBL8149234 | 0.77 | HCRTR2 (0.34) | MEN1ALDH1A1TSHRKMT2AEPHX1 | |
| SCHEMBL8145398 | 0.75 | EPHX1 (0.37) | MEN1ALDH1A1TSHRKMT2AEPHX1 | |
| SCHEMBL7727796 | 0.71 | P2RX7 (0.31) | P2RX7 | |
| SCHEMBL9076329 | 0.70 | MEN1 (0.33) | NPFFR1NPFFR2MEN1ALDH1A1TSHR | |
| SCHEMBL22874207 | 0.69 | CACNA1H (0.38) | NPFFR1NPFFR2MEN1ALDH1A1TSHR | |
| SCHEMBL2224543 | 0.69 | — | — | |
| SCHEMBL21409026 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000001714-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-01-13 | — | — | WO | disclosed |