Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7727840 | 1.00 | SIGMAR1 (0.52) | SIGMAR1ARPREPCXCR3AGTR2 | |
| SCHEMBL7727843 | 1.00 | SIGMAR1 (0.52) | SIGMAR1ARPREPCXCR3AGTR2 | |
| SCHEMBL7722009 | 0.82 | TGM2 (0.42) | SIGMAR1 | |
| SCHEMBL7722003 | 0.82 | TGM2 (0.42) | SIGMAR1 | |
| SCHEMBL7722007 | 0.82 | TGM2 (0.42) | SIGMAR1 | |
| SCHEMBL7730981 | 0.79 | MCL1 (0.45) | — | |
| SCHEMBL7730983 | 0.79 | MCL1 (0.45) | — | |
| SCHEMBL7730972 | 0.79 | MCL1 (0.45) | — | |
| SCHEMBL7722199 | 0.79 | NPFFR1 (0.43) | SIGMAR1AGTR2 | |
| SCHEMBL7722200 | 0.79 | NPFFR1 (0.43) | SIGMAR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399629-B1 | PYRROLIDINES AND PIPERIDINES FOR TREATING MICROBIAL INFECTIONS BY REDUCING EXPORT OF COADMINISTERED ANTIMICROBIAL AGENT OR COMPOUND SYNTHESIZED BY MICROBES FOR THEIR GROWTH; REDUCING IN VIVO AVAILABILITY | MICROCIDE PHARMACEUTICALS, INC. | 2002-06-04 | — | — | US | disclosed |