Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.45 |
| ▸ | YAP1 | P46937 | 3/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 5/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7730981 | 1.00 | MCL1 (0.45) | MCL1YAP1PRMT5KDM1AMAOA | |
| SCHEMBL7730983 | 1.00 | MCL1 (0.45) | MCL1YAP1PRMT5KDM1AMAOA | |
| SCHEMBL7722247 | 0.83 | STS (0.37) | — | |
| SCHEMBL7722098 | 0.83 | STS (0.37) | — | |
| SCHEMBL7727250 | 0.83 | LTA4H (0.45) | MCL1KDM1AMAOAMAOBGHSR | |
| SCHEMBL7722100 | 0.83 | STS (0.37) | — | |
| SCHEMBL7722091 | 0.83 | STS (0.37) | — | |
| SCHEMBL7727843 | 0.79 | SIGMAR1 (0.52) | — | |
| SCHEMBL7727833 | 0.79 | SIGMAR1 (0.52) | — | |
| SCHEMBL7727840 | 0.79 | SIGMAR1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399629-B1 | PYRROLIDINES AND PIPERIDINES FOR TREATING MICROBIAL INFECTIONS BY REDUCING EXPORT OF COADMINISTERED ANTIMICROBIAL AGENT OR COMPOUND SYNTHESIZED BY MICROBES FOR THEIR GROWTH; REDUCING IN VIVO AVAILABILITY | MICROCIDE PHARMACEUTICALS, INC. | 2002-06-04 | — | — | US | disclosed |