Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 9/20 | 0.38 |
| ▸ | MASP2 | O00187 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7723243 | 0.78 | CTSL (0.43) | CTSSCTSLCTSBCTSKNPC1 | |
| SCHEMBL7732434 | 0.77 | CTSL (0.43) | CTSSCTSLCTSBCTSKNPC1 | |
| SCHEMBL7728635 | 0.77 | F2 (0.35) | CTSSCTSLCTSBCTSKF2 | |
| SCHEMBL21436251 | 0.77 | F2 (0.35) | CTSSCTSLCTSBCTSKF2 | |
| Trifluoroacetic Acid SCHEMBL7732038 | 0.75 | CTSL (0.41) | CTSSCTSLCTSBCTSKNPC1 | |
| SCHEMBL21436289 | 0.74 | F2 (0.37) | CTSSCTSLCTSBCTSKF2 | |
| SCHEMBL21436586 | 0.74 | F2 (0.37) | CTSSCTSLCTSBCTSKF2 | |
| SCHEMBL8142222 | 0.74 | F2 (0.37) | CTSSCTSLCTSBCTSKF2 | |
| SCHEMBL21436588 | 0.74 | F2 (0.37) | CTSSCTSLCTSBCTSKF2 | |
| SCHEMBL7728949 | 0.74 | F2 (0.37) | CTSSCTSLCTSBCTSKF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399629-B1 | PYRROLIDINES AND PIPERIDINES FOR TREATING MICROBIAL INFECTIONS BY REDUCING EXPORT OF COADMINISTERED ANTIMICROBIAL AGENT OR COMPOUND SYNTHESIZED BY MICROBES FOR THEIR GROWTH; REDUCING IN VIVO AVAILABILITY | MICROCIDE PHARMACEUTICALS, INC. | 2002-06-04 | — | — | US | disclosed |