Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.43 |
| ▸ | CTSB | P07858 | 3/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7723017 | 0.86 | LMNA (0.45) | CTSLATMNPC1RAB9AMAPT | |
| SCHEMBL7734143 | 0.85 | ATM (0.46) | CTSLCTSBATM | |
| SCHEMBL7723243 | 0.81 | CTSL (0.43) | CTSLCTSBCTSSCTSKNPC1 | |
| SCHEMBL5731226 | 0.79 | CTSK (0.46) | CTSSCTSKATMRAB9AMAPT | |
| SCHEMBL5731227 | 0.79 | CTSK (0.46) | CTSSCTSKATMRAB9AMAPT | |
| Trifluoroacetic Acid SCHEMBL7732038 | 0.78 | CTSL (0.41) | CTSLCTSBCTSSCTSKNPC1 | |
| SCHEMBL7730692 | 0.78 | CTSL (0.42) | CTSLCTSBCTSSCTSKNPC1 | |
| SCHEMBL8066082 | 0.78 | TRPM8 (0.47) | CTSLCTSSCTSKATMNPC1 | |
| SCHEMBL6063007 | 0.77 | CTSL (0.51) | CTSLCTSBCTSSCTSK | |
| SCHEMBL12221562 | 0.77 | ATM (0.51) | ATMNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |